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Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates.
Bhat, Shreyas; Hasenhuetl, Peter S; Kasture, Ameya; El-Kasaby, Ali; Baumann, Michael H; Blough, Bruce E; Sucic, Sonja; Sandtner, Walter; Freissmuth, Michael.
Afiliação
  • Bhat S; From the Institute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, A-1090 Vienna, Austria.
  • Hasenhuetl PS; From the Institute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, A-1090 Vienna, Austria.
  • Kasture A; From the Institute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, A-1090 Vienna, Austria.
  • El-Kasaby A; From the Institute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, A-1090 Vienna, Austria.
  • Baumann MH; the Translational Pharmacology Section, Intramural Research Program, National Institute on Drug Abuse, Baltimore, Maryland 21224, and.
  • Blough BE; Center for Drug Discovery, Research Triangle Institute, Research Triangle Park, North Carolina 27709-1294.
  • Sucic S; From the Institute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, A-1090 Vienna, Austria.
  • Sandtner W; From the Institute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, A-1090 Vienna, Austria.
  • Freissmuth M; From the Institute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, A-1090 Vienna, Austria, michael.freissmuth@meduniwien.ac.at.
J Biol Chem ; 292(40): 16773-16786, 2017 10 06.
Article em En | MEDLINE | ID: mdl-28842491
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Chaperonas Moleculares / Proteínas da Membrana Plasmática de Transporte de Serotonina / Naftóis Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Chaperonas Moleculares / Proteínas da Membrana Plasmática de Transporte de Serotonina / Naftóis Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article