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Prediction of liver toxicity and mode of action using metabolomics in vitro in HepG2 cells.
Ramirez, Tzutzuy; Strigun, Alexander; Verlohner, Andreas; Huener, Hans-Albrecht; Peter, Erik; Herold, Michael; Bordag, Natalie; Mellert, Werner; Walk, Tilmann; Spitzer, Michael; Jiang, Xiaoqi; Sperber, Saskia; Hofmann, Thomas; Hartung, Thomas; Kamp, Hennicke; van Ravenzwaay, Ben.
Afiliação
  • Ramirez T; BASF SE Experimental Toxicology and Ecology, Carl-Bosch Str.38, 67056, Ludwigshafen Am Rhein, Germany.
  • Strigun A; Metanomics GmbH, Tegeler Weg 33, 10589, Berlin, Germany.
  • Verlohner A; BASF SE Experimental Toxicology and Ecology, Carl-Bosch Str.38, 67056, Ludwigshafen Am Rhein, Germany.
  • Huener HA; BASF SE Experimental Toxicology and Ecology, Carl-Bosch Str.38, 67056, Ludwigshafen Am Rhein, Germany.
  • Peter E; Metanomics GmbH, Tegeler Weg 33, 10589, Berlin, Germany.
  • Herold M; Metanomics GmbH, Tegeler Weg 33, 10589, Berlin, Germany.
  • Bordag N; Metanomics GmbH, Tegeler Weg 33, 10589, Berlin, Germany.
  • Mellert W; BASF SE Experimental Toxicology and Ecology, Carl-Bosch Str.38, 67056, Ludwigshafen Am Rhein, Germany.
  • Walk T; Metanomics GmbH, Tegeler Weg 33, 10589, Berlin, Germany.
  • Spitzer M; Metanomics GmbH, Tegeler Weg 33, 10589, Berlin, Germany.
  • Jiang X; BASF SE Experimental Toxicology and Ecology, Carl-Bosch Str.38, 67056, Ludwigshafen Am Rhein, Germany.
  • Sperber S; BASF SE Experimental Toxicology and Ecology, Carl-Bosch Str.38, 67056, Ludwigshafen Am Rhein, Germany.
  • Hofmann T; BASF SE Experimental Toxicology and Ecology, Carl-Bosch Str.38, 67056, Ludwigshafen Am Rhein, Germany. thomas.b.hofmann@basf.com.
  • Hartung T; Johns Hopkins Bloomberg School of Public Health, Center for Alternatives to Animal Testing (CAAT), Baltimore, MD, USA.
  • Kamp H; CAAT-Europe, University of Konstanz, Konstanz, Germany.
  • van Ravenzwaay B; BASF SE Experimental Toxicology and Ecology, Carl-Bosch Str.38, 67056, Ludwigshafen Am Rhein, Germany.
Arch Toxicol ; 92(2): 893-906, 2018 Feb.
Article em En | MEDLINE | ID: mdl-28965233
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Testes de Toxicidade / Metaboloma / Fígado Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Testes de Toxicidade / Metaboloma / Fígado Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article