Multiscale 3D Genome Rewiring during Mouse Neural Development.

Bonev, Boyan; Mendelson Cohen, Netta; Szabo, Quentin; Fritsch, Lauriane; Papadopoulos, Giorgio L; Lubling, Yaniv; Xu, Xiaole; Lv, Xiaodan; Hugnot, Jean-Philippe; Tanay, Amos; Cavalli, Giacomo

Bonev, Boyan; Mendelson Cohen, Netta; Szabo, Quentin; Fritsch, Lauriane; Papadopoulos, Giorgio L; Lubling, Yaniv; Xu, Xiaole; Lv, Xiaodan; Hugnot, Jean-Philippe; Tanay, Amos; Cavalli, Giacomo.

Afiliação

Bonev B; Institute of Human Genetics, UMR 9002 of the CNRS and the Université de Montpellier, 34396 Montpellier, France. Electronic address: boyan.bonev@igh.cnrs.fr.
Mendelson Cohen N; Weizmann Institute of Science, Rehovot 76100, Israel.
Szabo Q; Institute of Human Genetics, UMR 9002 of the CNRS and the Université de Montpellier, 34396 Montpellier, France.
Fritsch L; Institute of Human Genetics, UMR 9002 of the CNRS and the Université de Montpellier, 34396 Montpellier, France.
Papadopoulos GL; Institute of Human Genetics, UMR 9002 of the CNRS and the Université de Montpellier, 34396 Montpellier, France.
Lubling Y; Weizmann Institute of Science, Rehovot 76100, Israel.
Xu X; BGI, Shenzhen, 518083 Shenzhen, China.
Lv X; BGI, Shenzhen, 518083 Shenzhen, China.
Hugnot JP; INSERM U1051, Institute for Neurosciences, Hôpital Saint Eloi, Université de Montpellier 2, 34090 Montpellier, France.
Tanay A; Weizmann Institute of Science, Rehovot 76100, Israel.
Cavalli G; Institute of Human Genetics, UMR 9002 of the CNRS and the Université de Montpellier, 34396 Montpellier, France. Electronic address: giacomo.cavalli@igh.cnrs.fr.

Cell ; 171(3): 557-572.e24, 2017 Oct 19.

Article em En | MEDLINE | ID: mdl-29053968

Assuntos

Cromatina/metabolismo; Genoma; Neurogênese; Animais; Fator de Ligação a CCCTC; Células-Tronco Embrionárias/metabolismo; Elementos Facilitadores Genéticos; Éxons; Expressão Gênica; Redes Reguladoras de Genes; Camundongos; Regiões Promotoras Genéticas; Proteínas Repressoras/metabolismo; Fatores de Transcrição/metabolismo

Palavras-chave

3D genome architecture; Hi-C; Polycomb; cortical development; enhancers; neural differentiation; transcription; transcription factors

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromatina / Genoma / Neurogênese Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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