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A single rapamycin dose protects against late-stage experimental cerebral malaria via modulation of host immunity, endothelial activation and parasite sequestration.
Mejia, Pedro; Treviño-Villarreal, J Humberto; Reynolds, Justin S; De Niz, Mariana; Thompson, Andrew; Marti, Matthias; Mitchell, James R.
Afiliação
  • Mejia P; Department of Genetics and Complex Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, 02115, USA.
  • Treviño-Villarreal JH; Department of Genetics and Complex Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, 02115, USA.
  • Reynolds JS; Department of Genetics and Complex Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, 02115, USA.
  • De Niz M; Institute of Cell Biology, University of Bern, 3012, Bern, Switzerland.
  • Thompson A; Wellcome Center for Molecular Parasitology, University of Glasgow, Glasgow, G12 8TA, Scotland, UK.
  • Marti M; Rodent Histopathology Core, Harvard Medical School, Boston, MA, 02115, USA.
  • Mitchell JR; Wellcome Center for Molecular Parasitology, University of Glasgow, Glasgow, G12 8TA, Scotland, UK.
Malar J ; 16(1): 455, 2017 11 09.
Article em En | MEDLINE | ID: mdl-29121917

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium / Malária Cerebral / Sirolimo / Endotélio / Imunidade Adaptativa / Antimaláricos Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium / Malária Cerebral / Sirolimo / Endotélio / Imunidade Adaptativa / Antimaláricos Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article