Characterization of Pb51 in Plasmodium berghei as a malaria vaccine candidate targeting both asexual erythrocytic proliferation and transmission.

Wang, Jian; Zheng, Wenqi; Liu, Fei; Wang, Yaru; He, Yiwen; Zheng, Li; Fan, Qi; Luo, Enjie; Cao, Yaming; Cui, Liwang

Wang, Jian; Zheng, Wenqi; Liu, Fei; Wang, Yaru; He, Yiwen; Zheng, Li; Fan, Qi; Luo, Enjie; Cao, Yaming; Cui, Liwang.

Afiliação

Wang J; Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, 110001, Liaoning, China.
Zheng W; Laboratory of Surgery, The Affiliated Hospital, Inner Mongolia Medical University, Hohhot, 010050, China.
Liu F; Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, 110001, Liaoning, China.
Wang Y; Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, 110001, Liaoning, China.
He Y; Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, 110001, Liaoning, China.
Zheng L; Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, 110001, Liaoning, China.
Fan Q; Dalian Institute of Biotechnology, Dalian, Liaoning, China.
Luo E; Department of Pathogen Biology, College of Basic Medical Sciences, China Medical University, Shenyang, 110001, Liaoning, China.
Cao Y; Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, 110001, Liaoning, China. ymcao@mail.cmu.edu.cn.
Cui L; Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, 110001, Liaoning, China.

Malar J ; 16(1): 458, 2017 Nov 13.

Article em En | MEDLINE | ID: mdl-29132428

Assuntos

Vacinas Antimaláricas/imunologia; Malária/prevenção & controle; Plasmodium berghei/imunologia; Proteínas de Protozoários/genética; Animais; Western Blotting; Proliferação de Células/efeitos dos fármacos; Feminino; Técnica Indireta de Fluorescência para Anticorpo; Malária/parasitologia; Malária/transmissão; Camundongos; Camundongos Endogâmicos BALB C; Plasmodium berghei/genética; Proteínas de Protozoários/metabolismo; Coelhos

Palavras-chave

Asexual blood stage; Pb51; Plasmodium berghei; Sexual stage; Transmission-blocking; Vaccine candidate

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium berghei / Proteínas de Protozoários / Vacinas Antimaláricas / Malária Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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