Significance of various classes of anti-HBc in individuals with chronic asymptomatic HBV infection.
Am J Gastroenterol
; 84(2): 160-3, 1989 Feb.
Article
em En
| MEDLINE
| ID: mdl-2916527
ABSTRACT
Among 108 individuals with chronic asymptomatic hepatitis B virus infection, liver biopsies and serological investigation were performed simultaneously to determine the correlations of anti-HBc with the infection level of the liver pathology. The results showed that the prevalence of IgA and IgM anti-HBc, and the titers of IgA, IgM, and total anti-HBc, correlated with the liver damage. IgA anti-HBc was most prominent, being present in the whole group of patients with chronic active hepatitis with cirrhosis, and was absent in the whole group of asymptomatic carriers with normal histology. There were no linkages of IgA and IgM anti-HBc with the infectivity; in addition, the titer of total anti-HBc correlated inversely with the viral replication.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Hepatite B
/
Anticorpos Anti-Hepatite B
/
Antígenos do Núcleo do Vírus da Hepatite B
Tipo de estudo:
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1989
Tipo de documento:
Article