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Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and in Silico Techniques.
Di Lello, Paola; Pastor, Richard; Murray, Jeremy M; Blake, Robert A; Cohen, Frederick; Crawford, Terry D; Drobnick, Joy; Drummond, Jason; Kategaya, Lorna; Kleinheinz, Tracy; Maurer, Till; Rougé, Lionel; Zhao, Xianrui; Wertz, Ingrid; Ndubaku, Chudi; Tsui, Vickie.
Afiliação
  • Di Lello P; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Pastor R; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Murray JM; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Blake RA; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Cohen F; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Crawford TD; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Drobnick J; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Drummond J; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Kategaya L; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Kleinheinz T; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Maurer T; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Rougé L; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Zhao X; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Wertz I; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Ndubaku C; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Tsui V; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
J Med Chem ; 60(24): 10056-10070, 2017 12 28.
Article em En | MEDLINE | ID: mdl-29166018
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Bibliotecas de Moléculas Pequenas / Peptidase 7 Específica de Ubiquitina Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Bibliotecas de Moléculas Pequenas / Peptidase 7 Específica de Ubiquitina Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article