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Distribution of therapeutic proteins into thoracic lymph after intravenous administration is protein size-dependent and primarily occurs within the liver and mesentery.
Yadav, Preeti; McLeod, Victoria M; Nowell, Cameron J; Selby, Laura I; Johnston, Angus P R; Kaminskas, Lisa M; Trevaskis, Natalie L.
Afiliação
  • Yadav P; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus), 381 Royal Parade, Parkville, VIC 3052, Australia.
  • McLeod VM; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus), 381 Royal Parade, Parkville, VIC 3052, Australia; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC 3052, Australia.
  • Nowell CJ; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus), 381 Royal Parade, Parkville, VIC 3052, Australia.
  • Selby LI; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus), 381 Royal Parade, Parkville, VIC 3052, Australia; ARC Centre for Excellence in Convergent Bio-Nanoscience and Technology, Monash University (Parkville Campus), 381 Royal Parade
  • Johnston APR; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus), 381 Royal Parade, Parkville, VIC 3052, Australia; ARC Centre for Excellence in Convergent Bio-Nanoscience and Technology, Monash University (Parkville Campus), 381 Royal Parade
  • Kaminskas LM; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus), 381 Royal Parade, Parkville, VIC 3052, Australia; School of Biomedical Sciences, University of Queensland, St Lucia, QLD 4072, Australia.
  • Trevaskis NL; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus), 381 Royal Parade, Parkville, VIC 3052, Australia. Electronic address: Natalie.Trevaskis@monash.edu.
J Control Release ; 272: 17-28, 2018 02 28.
Article em En | MEDLINE | ID: mdl-29305921
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polietilenoglicóis / Interferons / Trastuzumab / Linfa Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polietilenoglicóis / Interferons / Trastuzumab / Linfa Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article