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Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism.
Kristensen, David Møbjerg; Desdoits-Lethimonier, Christèle; Mackey, Abigail L; Dalgaard, Marlene Danner; De Masi, Federico; Munkbøl, Cecilie Hurup; Styrishave, Bjarne; Antignac, Jean-Philippe; Le Bizec, Bruno; Platel, Christian; Hay-Schmidt, Anders; Jensen, Tina Kold; Lesné, Laurianne; Mazaud-Guittot, Séverine; Kristiansen, Karsten; Brunak, Søren; Kjaer, Michael; Juul, Anders; Jégou, Bernard.
Afiliação
  • Kristensen DM; Danish Headache Center, Department of Neurology, Rigshospitalet, University of Copenhagen, 1165 Copenhagen, Denmark.
  • Desdoits-Lethimonier C; Université de Rennes I, Inserm, EHESP-School of Public Health, Irset (Institut de Recherche en Santé, Environnement et Travail) - UMR_S 1085, F-35000 Rennes, France.
  • Mackey AL; Novo Nordisk Foundation Center for Protein Research Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3A, 2200 Copenhagen, Denmark.
  • Dalgaard MD; Université de Rennes I, Inserm, EHESP-School of Public Health, Irset (Institut de Recherche en Santé, Environnement et Travail) - UMR_S 1085, F-35000 Rennes, France.
  • De Masi F; Institute of Sports Medicine, Department of Orthopaedic Surgery M, Bispebjerg Hospital, 2400 Copenhagen NV, Denmark.
  • Munkbøl CH; Center for Healthy Aging, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 1165 Copenhagen, Denmark.
  • Styrishave B; DTU Bio and Health Informatics, Technical University of Denmark, 2800 Kongens Lyngby, Denmark.
  • Antignac JP; DTU Bio and Health Informatics, Technical University of Denmark, 2800 Kongens Lyngby, Denmark.
  • Le Bizec B; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, 1165 Copenhagen, Denmark.
  • Platel C; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, 1165 Copenhagen, Denmark.
  • Hay-Schmidt A; L'Université Nantes Angers Le Mans (LUNAM), Oniris, UMR 1329 INRA Laboratoire d'Etude des Résidus et Contaminants dans les Aliments (LABERCA), F-44307 Nantes, France.
  • Jensen TK; L'Université Nantes Angers Le Mans (LUNAM), Oniris, UMR 1329 INRA Laboratoire d'Etude des Résidus et Contaminants dans les Aliments (LABERCA), F-44307 Nantes, France.
  • Lesné L; Unité de coordination hospitalière des prélèvements d'organes et de tissus, Centre Hospitalier Universitaire de Rennes, 35000 Rennes, France.
  • Mazaud-Guittot S; Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, 1165 Copenhagen, Denmark.
  • Kristiansen K; Department of Environmental Medicine, University of Southern Denmark, 5000 Odense, Denmark.
  • Brunak S; Université de Rennes I, Inserm, EHESP-School of Public Health, Irset (Institut de Recherche en Santé, Environnement et Travail) - UMR_S 1085, F-35000 Rennes, France.
  • Kjaer M; Université de Rennes I, Inserm, EHESP-School of Public Health, Irset (Institut de Recherche en Santé, Environnement et Travail) - UMR_S 1085, F-35000 Rennes, France.
  • Juul A; Department of Biology, Faculty of Science, University of Copenhagen, 2100 Copenhagen, Denmark.
  • Jégou B; Institute of Metagenomics, BGI-Shenzhen, Shenzhen 518083, China.
Proc Natl Acad Sci U S A ; 115(4): E715-E724, 2018 01 23.
Article em En | MEDLINE | ID: mdl-29311296
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Testosterona / Hormônio Luteinizante / Ibuprofeno / Analgésicos não Narcóticos / Hipogonadismo Tipo de estudo: Clinical_trials Limite: Adult / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Testosterona / Hormônio Luteinizante / Ibuprofeno / Analgésicos não Narcóticos / Hipogonadismo Tipo de estudo: Clinical_trials Limite: Adult / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article