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7α,15-Dihydroxydehydroabietic acid from Pinus koraiensis inhibits the promotion of angiogenesis through downregulation of VEGF, p-Akt and p-ERK in HUVECs.
Lee, Tae Kyoung; Park, Jun Yeon; Yu, Jae Sik; Jang, Tae Su; Oh, Seong Taek; Pang, Changhyun; Ko, Yoon-Joo; Kang, Ki Sung; Kim, Ki Hyun.
Afiliação
  • Lee TK; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea.
  • Park JY; College of Korean Medicine, Gachon University, Seongnam 461-701, Republic of Korea.
  • Yu JS; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea.
  • Jang TS; Institute of Green Bio Science & Technology, Seoul National University, Pyeong Chang 232-916, Republic of Korea.
  • Oh ST; College of Pharmacy, Yeungnam University, Gyeongsan 38541, Republic of Korea.
  • Pang C; School of Chemical Engineering, Sungkyunkwan University, Suwon 440-746, Republic of Korea.
  • Ko YJ; Laboratory of Nucear Magnetic Resonance, National Center for Inter-University Research Facilities (NCIRF), Seoul National University, Gwanak-gu, Seoul 08826, Republic of Korea.
  • Kang KS; College of Korean Medicine, Gachon University, Seongnam 461-701, Republic of Korea. Electronic address: kkang@gachon.ac.kr.
  • Kim KH; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea. Electronic address: khkim83@skku.edu.
Bioorg Med Chem Lett ; 28(6): 1084-1089, 2018 04 01.
Article em En | MEDLINE | ID: mdl-29459209
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pinus / Abietanos / Fator A de Crescimento do Endotélio Vascular / MAP Quinases Reguladas por Sinal Extracelular / Proteínas Proto-Oncogênicas c-akt / Células Endoteliais da Veia Umbilical Humana / Neovascularização Patológica Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pinus / Abietanos / Fator A de Crescimento do Endotélio Vascular / MAP Quinases Reguladas por Sinal Extracelular / Proteínas Proto-Oncogênicas c-akt / Células Endoteliais da Veia Umbilical Humana / Neovascularização Patológica Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article