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The cryo-electron microscopy structure of huntingtin.
Guo, Qiang; Cheng, Jingdong; Seefelder, Manuel; Engler, Tatjana; Pfeifer, Günter; Oeckl, Patrick; Otto, Markus; Moser, Franziska; Maurer, Melanie; Pautsch, Alexander; Baumeister, Wolfgang; Fernández-Busnadiego, Rubén; Kochanek, Stefan.
Afiliação
  • Guo Q; Department of Molecular Structural Biology, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.
  • Bin Huang; Department of Gene Therapy, Ulm University, 89081 Ulm, Germany.
  • Cheng J; Gene Center, Department of Biochemistry and Center for Integrated Protein Science Munich, Ludwig-Maximilians University, 81377 Munich, Germany.
  • Seefelder M; Department of Gene Therapy, Ulm University, 89081 Ulm, Germany.
  • Engler T; Department of Gene Therapy, Ulm University, 89081 Ulm, Germany.
  • Pfeifer G; Department of Molecular Structural Biology, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.
  • Oeckl P; Department of Neurology, Ulm University, 89081 Ulm, Germany.
  • Otto M; Department of Neurology, Ulm University, 89081 Ulm, Germany.
  • Moser F; Department of Medicinal Chemistry, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach an der Riß, Germany.
  • Maurer M; Department of Medicinal Chemistry, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach an der Riß, Germany.
  • Pautsch A; Department of Medicinal Chemistry, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach an der Riß, Germany.
  • Baumeister W; Department of Molecular Structural Biology, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.
  • Fernández-Busnadiego R; Department of Molecular Structural Biology, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.
  • Kochanek S; Department of Gene Therapy, Ulm University, 89081 Ulm, Germany.
Nature ; 555(7694): 117-120, 2018 03 01.
Article em En | MEDLINE | ID: mdl-29466333

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Huntingtina Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Huntingtina Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article