[Research progress of CT/MRI parametric response map in precision evaluation of therapeutic response of cancer patients].

ABSTRACT

Intratumor spatial heterogeneity has been ignored in evaluating tumor therapeutic effect with conventional imaging methods. The voxel-based parametric response map (PRM) derived from CT or MRI may accurately, objectively and timely evaluate the tumor response to therapy, by comparing changes of the functional parameters before and after treatment. This approach may improve the imaging monitoring and the sensitivity of spatial resolution related to tumor changes after treatment. Thus, PRM may help to improve the treatment plan and prognosis evaluation for patients. This article reviews progress on CT/MRI PRM in precision evaluation of therapeutic response of cancer patients.