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A mechanistic pan-cancer pathway model informed by multi-omics data interprets stochastic cell fate responses to drugs and mitogens.
Bouhaddou, Mehdi; Barrette, Anne Marie; Stern, Alan D; Koch, Rick J; DiStefano, Matthew S; Riesel, Eric A; Santos, Luis C; Tan, Annie L; Mertz, Alex E; Birtwistle, Marc R.
Afiliação
  • Bouhaddou M; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
  • Barrette AM; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
  • Stern AD; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
  • Koch RJ; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
  • DiStefano MS; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
  • Riesel EA; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
  • Santos LC; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
  • Tan AL; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
  • Mertz AE; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
  • Birtwistle MR; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
PLoS Comput Biol ; 14(3): e1005985, 2018 03.
Article em En | MEDLINE | ID: mdl-29579036
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Biologia Computacional / Mitógenos / Neoplasias / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Biologia Computacional / Mitógenos / Neoplasias / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article