Combination of temperature shift and hydrolysate addition regulates anti-IgE monoclonal antibody charge heterogeneity in Chinese hamster ovary cell fed-batch culture.

Zheng, Chen; Zhuang, Chao; Qin, Jinyan; Chen, Yantian; Fu, Qiang; Qian, Hui; Wu, Tong; Wang, Yanchao; Wu, Xiang; Qi, Nianmin

Zheng, Chen; Zhuang, Chao; Qin, Jinyan; Chen, Yantian; Fu, Qiang; Qian, Hui; Wu, Tong; Wang, Yanchao; Wu, Xiang; Qi, Nianmin.

Afiliação

Zheng C; Cell Culture and Bioprocess Engineering Lab, School of Pharmacy, Shanghai Jiao Tong University, Dongchuan Road 800, Minhang District, Shanghai, 200240, China.
Zhuang C; Cell Culture and Bioprocess Engineering Lab, School of Pharmacy, Shanghai Jiao Tong University, Dongchuan Road 800, Minhang District, Shanghai, 200240, China.
Qin J; Shanghai Taiyin Biotech Co., Ltd., Shanghai, 201203, China.
Chen Y; School of Pharmacy, Wuhan University, Wuhan, 430072, China.
Fu Q; Cell Culture and Bioprocess Engineering Lab, School of Pharmacy, Shanghai Jiao Tong University, Dongchuan Road 800, Minhang District, Shanghai, 200240, China.
Qian H; Shanghai Taiyin Biotech Co., Ltd., Shanghai, 201203, China.
Wu T; Shanghai Taiyin Biotech Co., Ltd., Shanghai, 201203, China.
Wang Y; Cell Culture and Bioprocess Engineering Lab, School of Pharmacy, Shanghai Jiao Tong University, Dongchuan Road 800, Minhang District, Shanghai, 200240, China.
Wu X; Cell Culture and Bioprocess Engineering Lab, School of Pharmacy, Shanghai Jiao Tong University, Dongchuan Road 800, Minhang District, Shanghai, 200240, China.
Qi N; Shanghai Taiyin Biotech Co., Ltd., Shanghai, 201203, China.