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Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer.
Dasgupta, Subhamoy; Rajapakshe, Kimal; Zhu, Bokai; Nikolai, Bryan C; Yi, Ping; Putluri, Nagireddy; Choi, Jong Min; Jung, Sung Y; Coarfa, Cristian; Westbrook, Thomas F; Zhang, Xiang H-F; Foulds, Charles E; Tsai, Sophia Y; Tsai, Ming-Jer; O'Malley, Bert W.
Afiliação
  • Dasgupta S; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA. subhamoy.dasgupta@roswellpark.org.
  • Rajapakshe K; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA. subhamoy.dasgupta@roswellpark.org.
  • Zhu B; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
  • Nikolai BC; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
  • Yi P; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
  • Putluri N; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
  • Choi JM; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
  • Jung SY; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
  • Coarfa C; Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA.
  • Westbrook TF; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
  • Zhang XH; Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA.
  • Foulds CE; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
  • Tsai SY; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
  • Tsai MJ; Center for Precision Environmental Health, Baylor College of Medicine, Houston, TX, USA.
  • O'Malley BW; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
Nature ; 556(7700): 249-254, 2018 04.
Article em En | MEDLINE | ID: mdl-29615789
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Regulação Neoplásica da Expressão Gênica / Ativação Transcricional / Fosfofrutoquinase-2 / Coativador 3 de Receptor Nuclear / Glucose Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Regulação Neoplásica da Expressão Gênica / Ativação Transcricional / Fosfofrutoquinase-2 / Coativador 3 de Receptor Nuclear / Glucose Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article