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Synthesis and activity of di- or trisubstituted N-(phenoxyalkyl)- or N-{2-[2-(phenoxy)ethoxy]ethyl}piperazine derivatives on the central nervous system.
Panczyk, Katarzyna; Pytka, Karolina; Jakubczyk, Magdalena; Rapacz, Anna; Salat, Kinga; Furgala, Anna; Siwek, Agata; Gluch-Lutwin, Monika; Grybos, Anna; Sloczynska, Karolina; Pekala, Elzbieta; Zmudzki, Pawel; Bucki, Adam; Kolaczkowski, Marcin; Zelaszczyk, Dorota; Marona, Henryk; Waszkielewicz, Anna M.
Afiliação
  • Panczyk K; Department of Bioorganic Chemistry, Chair of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland. Electronic address: katarzyna.panczyk@uj.edu.pl.
  • Pytka K; Department of Pharmacodynamics, Chair of Pharmacodynamics, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
  • Jakubczyk M; Department of Pharmacodynamics, Chair of Pharmacodynamics, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
  • Rapacz A; Department of Pharmacodynamics, Chair of Pharmacodynamics, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
  • Salat K; Department of Pharmacodynamics, Chair of Pharmacodynamics, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
  • Furgala A; Department of Pharmacodynamics, Chair of Pharmacodynamics, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
  • Siwek A; Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
  • Gluch-Lutwin M; Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
  • Grybos A; Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
  • Sloczynska K; Department of Pharmaceutical Biochemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
  • Pekala E; Department of Pharmaceutical Biochemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
  • Zmudzki P; Department of Medicinal Chemistry, Chair of Pharmaceutical Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
  • Bucki A; Department of Medicinal Chemistry, Chair of Pharmaceutical Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
  • Kolaczkowski M; Department of Medicinal Chemistry, Chair of Pharmaceutical Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
  • Zelaszczyk D; Department of Bioorganic Chemistry, Chair of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
  • Marona H; Department of Bioorganic Chemistry, Chair of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
  • Waszkielewicz AM; Department of Bioorganic Chemistry, Chair of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
Bioorg Med Chem Lett ; 28(11): 2039-2049, 2018 06 15.
Article em En | MEDLINE | ID: mdl-29730027
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistema Nervoso Central / Receptores de Serotonina / Agonistas do Receptor de Serotonina / Piperazina / Atividade Motora / Anticonvulsivantes Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistema Nervoso Central / Receptores de Serotonina / Agonistas do Receptor de Serotonina / Piperazina / Atividade Motora / Anticonvulsivantes Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article