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Predominant Asymmetrical Stem Cell Fate Outcome Limits the Rate of Niche Succession in Human Colonic Crypts.
Stamp, Craig; Zupanic, Anze; Sachdeva, Ashwin; Stoll, Elizabeth A; Shanley, Daryl P; Mathers, John C; Kirkwood, Thomas B L; Heer, Rakesh; Simons, Benjamin D; Turnbull, Doug M; Greaves, Laura C.
Afiliação
  • Stamp C; LLHW Centre for Ageing and Vitality, Newcastle University Institute for Ageing, The Medical School, Newcastle upon Tyne NE2 4HH, UK; Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Zupanic A; Swiss Federal Institute of Aquatic Science and Technology, Department of Environmental Toxicology, Dübendorf, Switzerland.
  • Sachdeva A; Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK; Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne NE2 4AD, UK.
  • Stoll EA; Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Shanley DP; Institute of Cell and Molecular Biosciences, Newcastle University Institute for Ageing, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.
  • Mathers JC; LLHW Centre for Ageing and Vitality, Newcastle University Institute for Ageing, The Medical School, Newcastle upon Tyne NE2 4HH, UK; Human Nutrition Research Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.
  • Kirkwood TBL; Institute of Cell and Molecular Biosciences, Newcastle University Institute for Ageing, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.
  • Heer R; Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne NE2 4AD, UK.
  • Simons BD; Cavendish Laboratory, Department of Physics, University of Cambridge, J.J. Thomson Avenue, Cambridge CB3 0HE, UK; Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK; Wellcome Trust/Medical Research Council SC Institute, Cambridge CB2
  • Turnbull DM; LLHW Centre for Ageing and Vitality, Newcastle University Institute for Ageing, The Medical School, Newcastle upon Tyne NE2 4HH, UK; Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Greaves LC; LLHW Centre for Ageing and Vitality, Newcastle University Institute for Ageing, The Medical School, Newcastle upon Tyne NE2 4HH, UK; Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK. Electronic address: laura.greaves@ncl.ac.
EBioMedicine ; 31: 166-173, 2018 May.
Article em En | MEDLINE | ID: mdl-29748033

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco / Envelhecimento / Colo / Nicho de Células-Tronco / Mucosa Intestinal Limite: Adolescent / Adult / Aged / Aged80 / Humans / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco / Envelhecimento / Colo / Nicho de Células-Tronco / Mucosa Intestinal Limite: Adolescent / Adult / Aged / Aged80 / Humans / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article