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Dual tracer tau PET imaging reveals different molecular targets for 11C-THK5351 and 11C-PBB3 in the Alzheimer brain.
Chiotis, Konstantinos; Stenkrona, Per; Almkvist, Ove; Stepanov, Vladimir; Ferreira, Daniel; Arakawa, Ryosuke; Takano, Akihiro; Westman, Eric; Varrone, Andrea; Okamura, Nobuyuki; Shimada, Hitoshi; Higuchi, Makoto; Halldin, Christer; Nordberg, Agneta.
Afiliação
  • Chiotis K; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Translational Alzheimer Neurobiology, Karolinska Institutet, Stockholm, Sweden.
  • Stenkrona P; Department of Clinical Neuroscience, Center for Psychiatric Research, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden.
  • Almkvist O; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Translational Alzheimer Neurobiology, Karolinska Institutet, Stockholm, Sweden.
  • Stepanov V; Theme Aging, Karolinska University Hospital, Stockholm, Sweden.
  • Ferreira D; Department of Psychology, Stockholm University, Stockholm, Sweden.
  • Arakawa R; Department of Clinical Neuroscience, Center for Psychiatric Research, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden.
  • Takano A; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Clinical Geriatrics, Karolinska Institutet, Stockholm, Sweden.
  • Westman E; Department of Clinical Neuroscience, Center for Psychiatric Research, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden.
  • Varrone A; Department of Clinical Neuroscience, Center for Psychiatric Research, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden.
  • Okamura N; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Clinical Geriatrics, Karolinska Institutet, Stockholm, Sweden.
  • Shimada H; Department of Clinical Neuroscience, Center for Psychiatric Research, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden.
  • Higuchi M; Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan.
  • Halldin C; Division of Pharmacology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
  • Nordberg A; National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
Eur J Nucl Med Mol Imaging ; 45(9): 1605-1617, 2018 07.
Article em En | MEDLINE | ID: mdl-29752516
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinolinas / Proteínas tau / Tomografia por Emissão de Pósitrons / Doença de Alzheimer / Aminopiridinas Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinolinas / Proteínas tau / Tomografia por Emissão de Pósitrons / Doença de Alzheimer / Aminopiridinas Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Ano de publicação: 2018 Tipo de documento: Article