The serine/threonine protein kinase of Streptococcus suis serotype 2 affects the ability of the pathogen to penetrate the blood-brain barrier.

Rui, Liu; Weiyi, Li; Yu, Meng; Hong, Zhou; Jiao, Yu; Zhe, Ma; Hongjie, Fan

Rui, Liu; Weiyi, Li; Yu, Meng; Hong, Zhou; Jiao, Yu; Zhe, Ma; Hongjie, Fan.

Afiliação

Rui L; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Weiyi L; Jiangsu Academy of Agricultural Sciences, Veterinary Research Institute, Nanjing, China.
Yu M; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Hong Z; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Jiao Y; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Zhe M; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Hongjie F; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.

Cell Microbiol ; 20(10): e12862, 2018 10.

Article em En | MEDLINE | ID: mdl-29797543

Assuntos

Barreira Hematoencefálica/microbiologia; Claudina-5/metabolismo; Meningites Bacterianas/patologia; Receptores Proteína Tirosina Quinases/genética; Streptococcus suis/genética; Ubiquitina-Proteína Ligases/metabolismo; Animais; Claudina-5/antagonistas & inibidores; Claudina-5/genética; Elementos de DNA Transponíveis/genética; Meningites Bacterianas/microbiologia; Camundongos; Camundongos Endogâmicos BALB C; Streptococcus suis/patogenicidade; Suínos; Ubiquitinação/genética; Virulência/genética; Fatores de Virulência/genética

Palavras-chave

E3 ubiquitin ligase HECTD1; Streptococcus suis serotype 2; blood-brain barrier; claudin-5; serine/threonine protein kinase; ubiquitination

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Barreira Hematoencefálica / Streptococcus suis / Meningites Bacterianas / Receptores Proteína Tirosina Quinases / Ubiquitina-Proteína Ligases / Claudina-5 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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