Use of Favipiravir to Treat Lassa Virus Infection in Macaques.
Emerg Infect Dis
; 24(9): 1696-1699, 2018 09.
Article
em En
| MEDLINE
| ID: mdl-29882740
ABSTRACT
Lassa virus, the cause of Lassa fever in humans, is endemic to West Africa. Treatment of Lassa fever is primarily supportive, although ribavirin has shown limited efficacy if administered early during infection. We tested favipiravir in Lassa virus-viremic macaques and found that 300 mg/kg daily for 2 weeks successfully treated infection.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Pirazinas
/
Amidas
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Febre Lassa
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Vírus Lassa
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Macaca
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Doenças dos Macacos
Limite:
Animals
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article