CancerDetector: ultrasensitive and non-invasive cancer detection at the resolution of individual reads using cell-free DNA methylation sequencing data.

Li, Wenyuan; Li, Qingjiao; Kang, Shuli; Same, Mary; Zhou, Yonggang; Sun, Carol; Liu, Chun-Chi; Matsuoka, Lea; Sher, Linda; Wong, Wing Hung; Alber, Frank; Zhou, Xianghong Jasmine

Li, Wenyuan; Li, Qingjiao; Kang, Shuli; Same, Mary; Zhou, Yonggang; Sun, Carol; Liu, Chun-Chi; Matsuoka, Lea; Sher, Linda; Wong, Wing Hung; Alber, Frank; Zhou, Xianghong Jasmine.

Afiliação

Li W; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90095, USA.
Li Q; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90095, USA.
Kang S; Molecular and Computational Biology Program, Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Same M; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90095, USA.
Zhou Y; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90095, USA.
Sun C; Oak Park High School, Oak Park, CA 91377, USA.
Liu CC; Institute of Genomics and Bioinformatics, National Chung Hsing University, Taiwan 40227, Republic of China.
Matsuoka L; Division of Hepatobiliary Surgery & Liver Transplantation, Department of Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Sher L; Department of Surgery, University of Southern California, Keck School of Medicine, Los Angeles, Los Angeles, CA 90033, USA.
Wong WH; Department of Statistics, Stanford University, Stanford, CA 94305, USA.
Alber F; Department of Health Research & Policy, Stanford University, Stanford, CA 94305, USA.
Zhou XJ; Molecular and Computational Biology Program, Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA.

Nucleic Acids Res ; 46(15): e89, 2018 09 06.

Article em En | MEDLINE | ID: mdl-29897492

Assuntos

Algoritmos; Ácidos Nucleicos Livres/genética; Biologia Computacional/métodos; Metilação de DNA; Neoplasias/diagnóstico; Ácidos Nucleicos Livres/química; Ilhas de CpG/genética; DNA de Neoplasias/química; DNA de Neoplasias/genética; Sequenciamento de Nucleotídeos em Larga Escala/métodos; Humanos; Neoplasias/sangue; Neoplasias/genética; Curva ROC; Reprodutibilidade dos Testes

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Algoritmos / Biologia Computacional / Metilação de DNA / Ácidos Nucleicos Livres / Neoplasias Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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