Down-regulation of microsomal prostaglandin E2 synthase-1 in the infrapatellar fat pad of osteoarthritis patients with hypercholesterolemia.

Mukai, Manabu; Uchida, Kentaro; Takano, Shotaro; Iwase, Dai; Aikawa, Jun; Inoue, Gen; Miyagi, Masayuki; Takaso, Masashi

Mukai, Manabu; Uchida, Kentaro; Takano, Shotaro; Iwase, Dai; Aikawa, Jun; Inoue, Gen; Miyagi, Masayuki; Takaso, Masashi.

Afiliação

Mukai M; Department of Orthopedic Surgery, Kitasato University School of Medicine, 1-15-1 Minami-ku Kitasato, Sagamihara City, Kanagawa, 252-0374, Japan.
Uchida K; Department of Orthopedic Surgery, Kitasato University School of Medicine, 1-15-1 Minami-ku Kitasato, Sagamihara City, Kanagawa, 252-0374, Japan. kuchida@med.kitasato-u.ac.jp.
Takano S; Department of Orthopedic Surgery, Kitasato University School of Medicine, 1-15-1 Minami-ku Kitasato, Sagamihara City, Kanagawa, 252-0374, Japan.
Iwase D; Department of Orthopedic Surgery, Kitasato University School of Medicine, 1-15-1 Minami-ku Kitasato, Sagamihara City, Kanagawa, 252-0374, Japan.
Aikawa J; Department of Orthopedic Surgery, Kitasato University School of Medicine, 1-15-1 Minami-ku Kitasato, Sagamihara City, Kanagawa, 252-0374, Japan.
Inoue G; Department of Orthopedic Surgery, Kitasato University School of Medicine, 1-15-1 Minami-ku Kitasato, Sagamihara City, Kanagawa, 252-0374, Japan.
Miyagi M; Department of Orthopedic Surgery, Kitasato University School of Medicine, 1-15-1 Minami-ku Kitasato, Sagamihara City, Kanagawa, 252-0374, Japan.
Takaso M; Department of Orthopedic Surgery, Kitasato University School of Medicine, 1-15-1 Minami-ku Kitasato, Sagamihara City, Kanagawa, 252-0374, Japan.

Lipids Health Dis ; 17(1): 137, 2018 Jun 13.

Article em En | MEDLINE | ID: mdl-29898737

Assuntos

Tecido Adiposo/metabolismo; Colesterol/metabolismo; Hipercolesterolemia/genética; Osteoartrite do Joelho/genética; Prostaglandina-E Sintases/genética; Idoso; Idoso de 80 Anos ou mais; Artroplastia do Joelho; Ciclo-Oxigenase 2/genética; Ciclo-Oxigenase 2/metabolismo; Feminino; Regulação da Expressão Gênica; Humanos; Hipercolesterolemia/metabolismo; Hipercolesterolemia/patologia; Hipercolesterolemia/cirurgia; Interleucina-1beta/genética; Interleucina-1beta/metabolismo; Interleucina-6/genética; Interleucina-6/metabolismo; Cápsula Articular/metabolismo; Masculino; Osteoartrite do Joelho/metabolismo; Osteoartrite do Joelho/patologia; Osteoartrite do Joelho/cirurgia; Patela/metabolismo; Prostaglandina-E Sintases/metabolismo; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Fator de Necrose Tumoral alfa/genética; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

Hypercholesterolemia; Infrapatellar fat pad; Microsomal prostaglandin E2 synthase-1

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tecido Adiposo / Colesterol / Osteoartrite do Joelho / Prostaglandina-E Sintases / Hipercolesterolemia Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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