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MEDI0382, a GLP-1/glucagon receptor dual agonist, meets safety and tolerability endpoints in a single-dose, healthy-subject, randomized, Phase 1 study.
Ambery, Philip D; Klammt, Sebastian; Posch, Maximillian G; Petrone, Marcella; Pu, Wenji; Rondinone, Cristina; Jermutus, Lutz; Hirshberg, Boaz.
Afiliação
  • Ambery PD; Cardiovascular, Renal, and Metabolism iMED, MedImmune Ltd, Cambridge, UK.
  • Klammt S; Charité Research Organisation GmbH, Berlin, Germany.
  • Posch MG; Charité Research Organisation GmbH, Berlin, Germany.
  • Petrone M; Cardiovascular, Renal, and Metabolism iMED, MedImmune Ltd, Cambridge, UK.
  • Pu W; Cardiovascular, Renal, and Metabolism iMED, MedImmune Inc, Gaithersburg, MD, USA.
  • Rondinone C; Cardiovascular, Renal, and Metabolism iMED, MedImmune Inc, Gaithersburg, MD, USA.
  • Jermutus L; Cardiovascular, Renal, and Metabolism iMED, MedImmune Ltd, Cambridge, UK.
  • Hirshberg B; Cardiovascular, Renal, and Metabolism iMED, MedImmune Inc, Gaithersburg, MD, USA.
Br J Clin Pharmacol ; 84(10): 2325-2335, 2018 10.
Article em En | MEDLINE | ID: mdl-29926478
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Hipoglicemiantes Tipo de estudo: Clinical_trials Limite: Adult / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Hipoglicemiantes Tipo de estudo: Clinical_trials Limite: Adult / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article