Copper-catalyzed cyclization of 2-cyanobenzaldehydes and 2-isocyanoacetates: an efficient strategy for the synthesis of substituted 1-aminoisoquinolines.
Chem Commun (Camb)
; 54(59): 8194-8197, 2018 Jul 19.
Article
em En
| MEDLINE
| ID: mdl-29975389
ABSTRACT
A Cu(acac)2-catalyzed cyclization reaction of 2-cyanobenzaldehydes with 2-isocyanoacetates has been successfully developed providing an efficient strategy for the synthesis of substituted 1-aminoisoquinolines. The reaction proceeds smoothly under mild conditions with high efficiency, and might provide an alternative strategy for the synthesis of 1-aminoisoquinoline containing molecules.
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MEDLINE
Idioma:
En
Ano de publicação:
2018
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Article