Improvement in clinical outcomes and replacement factor VIII use in patients with haemophilia A after factor VIII pharmacokinetic-guided prophylaxis based on Bayesian models with myPKFiT<sup>®</sup>.

Mingot-Castellano, M E; Parra, R; Núñez, R; Martorell, M

Improvement in clinical outcomes and replacement factor VIII use in patients with haemophilia A after factor VIII pharmacokinetic-guided prophylaxis based on Bayesian models with myPKFiT^®.

Mingot-Castellano, M E; Parra, R; Núñez, R; Martorell, M.

Afiliação

Mingot-Castellano ME; Hospital Regional Universitario de Málaga, Málaga, Spain.
Parra R; Hospital de la Vall d'Hebron, Barcelona, Spain.
Núñez R; Hospital Universitario Virgen del Rocío, Seville, Spain.
Martorell M; Hospital de la Vall d'Hebron, Barcelona, Spain.

Haemophilia ; 24(5): e338-e343, 2018 Sep.

Article em En | MEDLINE | ID: mdl-30028549

Assuntos

Fator VIII/uso terapêutico; Hemofilia A/tratamento farmacológico; Adolescente; Adulto; Teorema de Bayes; Criança; Fator VIII/farmacocinética; Feminino; Humanos; Masculino; Pessoa de Meia-Idade; Adulto Jovem

Palavras-chave

Bayesian models; annual bleeding rate; factor VIII; haemophilia A; pharmacokinetic adjustment; prophylaxis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator VIII / Hemofilia A Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies / Qualitative_research Limite: Adolescent / Adult / Child / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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