Strikingly Different Atheroprotective Effects of Apolipoprotein A-I in Early- Versus Late-Stage Atherosclerosis.

Strikingly Different Atheroprotective Effects of Apolipoprotein A-I in Early- Versus Late-Stage Atherosclerosis.

Morton, Jamie; Bao, Shisan; Vanags, Laura Z; Tsatralis, Tania; Ridiandries, Anisyah; Siu, Chung-Wah; Ng, Kwong-Man; Tan, Joanne T M; Celermajer, David S; Ng, Martin K C; Bursill, Christina A.

Afiliação

Morton J; Immunobiology Group, The Heart Research Institute, Sydney, Australia.
Bao S; Department of Medicine, Sydney Medical School, University of Sydney, Sydney, Australia.
Vanags LZ; Discipline of Pathology, University of Sydney, Sydney, Australia.
Tsatralis T; Immunobiology Group, The Heart Research Institute, Sydney, Australia.
Ridiandries A; Department of Medicine, Sydney Medical School, University of Sydney, Sydney, Australia.
Siu CW; Immunobiology Group, The Heart Research Institute, Sydney, Australia.
Ng KM; Immunobiology Group, The Heart Research Institute, Sydney, Australia.
Tan JTM; Department of Medicine, Sydney Medical School, University of Sydney, Sydney, Australia.
Celermajer DS; Division of Cardiology, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.
Ng MKC; Division of Cardiology, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.
Bursill CA; Immunobiology Group, The Heart Research Institute, Sydney, Australia.

JACC Basic Transl Sci ; 3(2): 187-199, 2018 Apr.

Article em En | MEDLINE | ID: mdl-30062204

Palavras-chave

Bcl-xL, B-cell lymphoma-extra large; HCAEC, human coronary artery endothelial cell; HDL, high-density lipoprotein; HFD, high-fat diet; LDL, low-density lipoprotein; LVApoAI, lentivirus overexpressing apolipoprotein A-I; LVGFP, lentivirus overexpressing green fluorescence protein; MCP, monocyte chemoattractant protein; SAA, serum amyloid amylase; SMC, smooth muscle cell; SNP, single-nucleotide polymorphism; TNF, tumor necrosis factor; VCAM, vascular cell adhesion molecule; apoA-I, apolipoprotein A-I; apoE−/−, apolipoprotein E deficient; atherosclerosis; cholesterol; high-density lipoproteins; micro-CT, micro-computed tomography; rHDL, reconstituted high-density lipoprotein

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article