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KDM5 histone demethylases repress immune response via suppression of STING.
Wu, Lizhen; Cao, Jian; Cai, Wesley L; Lang, Sabine M; Horton, John R; Jansen, Daniel J; Liu, Zongzhi Z; Chen, Jocelyn F; Zhang, Meiling; Mott, Bryan T; Pohida, Katherine; Rai, Ganesha; Kales, Stephen C; Henderson, Mark J; Hu, Xin; Jadhav, Ajit; Maloney, David J; Simeonov, Anton; Zhu, Shu; Iwasaki, Akiko; Hall, Matthew D; Cheng, Xiaodong; Shadel, Gerald S; Yan, Qin.
Afiliação
  • Wu L; Department of Pathology, Yale School of Medicine, New Haven, Connecticut, United States of America.
  • Cao J; Department of Pathology, Yale School of Medicine, New Haven, Connecticut, United States of America.
  • Cai WL; Department of Pathology, Yale School of Medicine, New Haven, Connecticut, United States of America.
  • Lang SM; Department of Pathology, Yale School of Medicine, New Haven, Connecticut, United States of America.
  • Horton JR; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
  • Jansen DJ; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
  • Liu ZZ; Department of Pathology, Yale School of Medicine, New Haven, Connecticut, United States of America.
  • Chen JF; Department of Pathology, Yale School of Medicine, New Haven, Connecticut, United States of America.
  • Zhang M; Department of Pathology, Yale School of Medicine, New Haven, Connecticut, United States of America.
  • Mott BT; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
  • Pohida K; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
  • Rai G; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
  • Kales SC; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
  • Henderson MJ; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
  • Hu X; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
  • Jadhav A; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
  • Maloney DJ; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
  • Simeonov A; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
  • Zhu S; Institute of Immunology and the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science and Technology of China, Hefei, China.
  • Iwasaki A; Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut, United States of America.
  • Hall MD; Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America.
  • Cheng X; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
  • Shadel GS; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
  • Yan Q; Department of Pathology, Yale School of Medicine, New Haven, Connecticut, United States of America.
PLoS Biol ; 16(8): e2006134, 2018 08.
Article em En | MEDLINE | ID: mdl-30080846

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Proteínas Nucleares / Histona Desmetilases / Histona Desmetilases com o Domínio Jumonji / Proteínas de Membrana Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Proteínas Nucleares / Histona Desmetilases / Histona Desmetilases com o Domínio Jumonji / Proteínas de Membrana Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article