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Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes.
Alexandrou, Constantinos; Al-Aqbi, Saif Sattar; Higgins, Jennifer A; Boyle, William; Karmokar, Ankur; Andreadi, Catherine; Luo, Jin-Li; Moore, David A; Viskaduraki, Maria; Blades, Matthew; Murray, Graeme I; Howells, Lynne M; Thomas, Anne; Brown, Karen; Cheng, Paul N; Rufini, Alessandro.
Afiliação
  • Alexandrou C; Department of Genetics and Genome Biology, Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 7LX, UK.
  • Al-Aqbi SS; Department of Genetics and Genome Biology, Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 7LX, UK.
  • Higgins JA; Department of Pathology and Poultry Diseases, Faculty of Veterinary Medicine, University of Kufa, Kufa, Iraq.
  • Boyle W; Department of Genetics and Genome Biology, Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 7LX, UK.
  • Karmokar A; Birmingham Women's Hospital, Birmingham, B15 2TG, UK.
  • Andreadi C; Department of Genetics and Genome Biology, Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 7LX, UK.
  • Luo JL; Department of Genetics and Genome Biology, Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 7LX, UK.
  • Moore DA; Department of Genetics and Genome Biology, Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 7LX, UK.
  • Viskaduraki M; Department of Pathology, UCL Cancer Centre, UCL, London, UK.
  • Blades M; Bioinformatics and Biostatistics Support Hub, University of Leicester, Leicester, LE1 7RH, UK.
  • Murray GI; Bioinformatics and Biostatistics Support Hub, University of Leicester, Leicester, LE1 7RH, UK.
  • Howells LM; Department of Pathology, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Foresterhill, Aberdeen, AB25, 2ZD, UK.
  • Thomas A; Department of Genetics and Genome Biology, Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 7LX, UK.
  • Brown K; Department of Genetics and Genome Biology, Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 7LX, UK.
  • Cheng PN; Department of Genetics and Genome Biology, Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 7LX, UK.
  • Rufini A; Bio-Cancer Treatment International Limited, Hong Kong, Hong Kong.
Sci Rep ; 8(1): 12096, 2018 08 14.
Article em En | MEDLINE | ID: mdl-30108309
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Arginina / Argininossuccinato Sintase / Neoplasias Colorretais / Protocolos de Quimioterapia Combinada Antineoplásica Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Arginina / Argininossuccinato Sintase / Neoplasias Colorretais / Protocolos de Quimioterapia Combinada Antineoplásica Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article