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Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction.
Lin, Edward Y S; Silvian, Laura F; Marcotte, Douglas J; Banos, Charles C; Jow, Flora; Chan, Timothy R; Arduini, Robert M; Qian, Fang; Baker, Darren P; Bergeron, Chris; Hession, Catherine A; Huganir, Richard L; Borenstein, Cassandra F; Enyedy, Istvan; Zou, Jinming; Rohde, Ellen; Wittmann, Marion; Kumaravel, Gnanasambandam; Rhodes, Kenneth J; Scannevin, Robert H; Dunah, Anthone W; Guckian, Kevin M.
Afiliação
  • Lin EYS; Biotherapeutics and Medicinal Sciences, Biogen Inc, Cambridge, Massachusetts, USA.
  • Silvian LF; Biotherapeutics and Medicinal Sciences, Biogen Inc, Cambridge, Massachusetts, USA.
  • Marcotte DJ; Biotherapeutics and Medicinal Sciences, Biogen Inc, Cambridge, Massachusetts, USA.
  • Banos CC; Alzheimer's Disease and Dementia Research Unit, Biogen Inc, Cambridge, Massachusetts, USA.
  • Jow F; Alzheimer's Disease and Dementia Research Unit, Biogen Inc, Cambridge, Massachusetts, USA.
  • Chan TR; Biotherapeutics and Medicinal Sciences, Biogen Inc, Cambridge, Massachusetts, USA.
  • Arduini RM; Biotherapeutics and Medicinal Sciences, Biogen Inc, Cambridge, Massachusetts, USA.
  • Qian F; Biotherapeutics and Medicinal Sciences, Biogen Inc, Cambridge, Massachusetts, USA.
  • Baker DP; Biotherapeutics and Medicinal Sciences, Biogen Inc, Cambridge, Massachusetts, USA.
  • Bergeron C; Biotherapeutics and Medicinal Sciences, Biogen Inc, Cambridge, Massachusetts, USA.
  • Hession CA; Biotherapeutics and Medicinal Sciences, Biogen Inc, Cambridge, Massachusetts, USA.
  • Huganir RL; Department of Neuroscience and Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Borenstein CF; Biotherapeutics and Medicinal Sciences, Biogen Inc, Cambridge, Massachusetts, USA.
  • Enyedy I; Biotherapeutics and Medicinal Sciences, Biogen Inc, Cambridge, Massachusetts, USA.
  • Zou J; Biotherapeutics and Medicinal Sciences, Biogen Inc, Cambridge, Massachusetts, USA.
  • Rohde E; Biotherapeutics and Medicinal Sciences, Biogen Inc, Cambridge, Massachusetts, USA.
  • Wittmann M; Alzheimer's Disease and Dementia Research Unit, Biogen Inc, Cambridge, Massachusetts, USA.
  • Kumaravel G; Biotherapeutics and Medicinal Sciences, Biogen Inc, Cambridge, Massachusetts, USA.
  • Rhodes KJ; Alzheimer's Disease and Dementia Research Unit, Biogen Inc, Cambridge, Massachusetts, USA.
  • Scannevin RH; Alzheimer's Disease and Dementia Research Unit, Biogen Inc, Cambridge, Massachusetts, USA.
  • Dunah AW; Alzheimer's Disease and Dementia Research Unit, Biogen Inc, Cambridge, Massachusetts, USA.
  • Guckian KM; Biotherapeutics and Medicinal Sciences, Biogen Inc, Cambridge, Massachusetts, USA. kevin.guckian@biogen.com.
Sci Rep ; 8(1): 13438, 2018 09 07.
Article em En | MEDLINE | ID: mdl-30194389
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sinapses / Encéfalo / Proteínas Nucleares / Proteínas de Transporte / Peptídeos beta-Amiloides / Doenças Neurodegenerativas / Espinhas Dendríticas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sinapses / Encéfalo / Proteínas Nucleares / Proteínas de Transporte / Peptídeos beta-Amiloides / Doenças Neurodegenerativas / Espinhas Dendríticas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article