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Optimized arylomycins are a new class of Gram-negative antibiotics.
Smith, Peter A; Koehler, Michael F T; Girgis, Hany S; Yan, Donghong; Chen, Yongsheng; Chen, Yuan; Crawford, James J; Durk, Matthew R; Higuchi, Robert I; Kang, Jing; Murray, Jeremy; Paraselli, Prasuna; Park, Summer; Phung, Wilson; Quinn, John G; Roberts, Tucker C; Rougé, Lionel; Schwarz, Jacob B; Skippington, Elizabeth; Wai, John; Xu, Min; Yu, Zhiyong; Zhang, Hua; Tan, Man-Wah; Heise, Christopher E.
Afiliação
  • Smith PA; Department of Infectious Diseases, Genentech, South San Francisco, CA, USA. smith.peter@gene.com.
  • Koehler MFT; Department of Discovery Chemistry, Genentech, South San Francisco, CA, USA.
  • Girgis HS; Department of Infectious Diseases, Genentech, South San Francisco, CA, USA.
  • Yan D; Department of Translational Immunology, Genentech, South San Francisco, CA, USA.
  • Chen Y; Department of Chemistry, Wuxi AppTec, Shanghai, China.
  • Chen Y; Department of Drug Metabolism and Pharmacokinetics, Genentech, South San Francisco, CA, USA.
  • Crawford JJ; Department of Discovery Chemistry, Genentech, South San Francisco, CA, USA.
  • Durk MR; Department of Drug Metabolism and Pharmacokinetics, Genentech, South San Francisco, CA, USA.
  • Higuchi RI; RQx Pharmaceuticals, La Jolla, CA, USA.
  • Kang J; Retrovirox, San Diego, CA, USA.
  • Murray J; Department of Translational Immunology, Genentech, South San Francisco, CA, USA.
  • Paraselli P; Department of Structural Biology, Genentech, South San Francisco, CA, USA.
  • Park S; RQx Pharmaceuticals, La Jolla, CA, USA.
  • Phung W; Vertex, San Diego, CA, USA.
  • Quinn JG; Department of Translational Immunology, Genentech, South San Francisco, CA, USA.
  • Roberts TC; Department of Microchem Proteomics, Genentech, South San Francisco, CA, USA.
  • Rougé L; Department of Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA, USA.
  • Schwarz JB; RQx Pharmaceuticals, La Jolla, CA, USA.
  • Skippington E; Aduro Biotech, Berkeley, CA, USA.
  • Wai J; Department of Structural Biology, Genentech, South San Francisco, CA, USA.
  • Xu M; Department of Discovery Chemistry, Genentech, South San Francisco, CA, USA.
  • Yu Z; FLX Bio, South San Francisco, CA, USA.
  • Zhang H; Department of Bioinformatics and Computational Biology, Genentech, South San Francisco, CA, USA.
  • Tan MW; Department of Chemistry, Wuxi AppTec, Shanghai, China.
  • Heise CE; Department of Translational Immunology, Genentech, South San Francisco, CA, USA.
Nature ; 561(7722): 189-194, 2018 09.
Article em En | MEDLINE | ID: mdl-30209367
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Bactérias Gram-Negativas / Antibacterianos Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Bactérias Gram-Negativas / Antibacterianos Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article