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In situ identification of Gram-negative bacteria in human lungs using a topical fluorescent peptide targeting lipid A.
Akram, Ahsan R; Chankeshwara, Sunay V; Scholefield, Emma; Aslam, Tashfeen; McDonald, Neil; Megia-Fernandez, Alicia; Marshall, Adam; Mills, Bethany; Avlonitis, Nicolaos; Craven, Thomas H; Smyth, Annya M; Collie, David S; Gray, Calum; Hirani, Nik; Hill, Adam T; Govan, John R; Walsh, Timothy; Haslett, Christopher; Bradley, Mark; Dhaliwal, Kevin.
Afiliação
  • Akram AR; EPSRC IRC PROTEUS Hub, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK. kev.dhaliwal@ed.ac.uk mark.bradley@ed.ac.uk ahsan.akram@ed.ac.uk.
  • Chankeshwara SV; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
  • Scholefield E; EPSRC IRC PROTEUS Hub, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
  • Aslam T; EaStCHEM, University of Edinburgh School of Chemistry, Joseph Black Building, West Mains Road, Edinburgh EH9 3FJ, UK.
  • McDonald N; EPSRC IRC PROTEUS Hub, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
  • Megia-Fernandez A; EaStCHEM, University of Edinburgh School of Chemistry, Joseph Black Building, West Mains Road, Edinburgh EH9 3FJ, UK.
  • Marshall A; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
  • Mills B; EPSRC IRC PROTEUS Hub, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
  • Avlonitis N; EaStCHEM, University of Edinburgh School of Chemistry, Joseph Black Building, West Mains Road, Edinburgh EH9 3FJ, UK.
  • Craven TH; EPSRC IRC PROTEUS Hub, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
  • Smyth AM; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
  • Collie DS; EPSRC IRC PROTEUS Hub, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
  • Gray C; EaStCHEM, University of Edinburgh School of Chemistry, Joseph Black Building, West Mains Road, Edinburgh EH9 3FJ, UK.
  • Hirani N; EPSRC IRC PROTEUS Hub, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
  • Hill AT; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
  • Govan JR; EPSRC IRC PROTEUS Hub, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
  • Walsh T; The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian EH25 9RG, UK.
  • Haslett C; Clinical Research Imaging Facility, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
  • Bradley M; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
  • Dhaliwal K; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
Sci Transl Med ; 10(464)2018 10 24.
Article em En | MEDLINE | ID: mdl-30355797
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Corantes Fluorescentes / Bactérias Gram-Negativas / Lipídeo A / Pulmão Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Corantes Fluorescentes / Bactérias Gram-Negativas / Lipídeo A / Pulmão Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article