Ski drives an acute increase in MMP-9 gene expression and release in primary cardiac myofibroblasts.

Landry, Natalie; Kavosh, Morvarid S; Filomeno, Krista L; Rattan, Sunil G; Czubryt, Michael P; Dixon, Ian M C

Ski drives an acute increase in MMP-9 gene expression and release in primary cardiac myofibroblasts.

Landry, Natalie; Kavosh, Morvarid S; Filomeno, Krista L; Rattan, Sunil G; Czubryt, Michael P; Dixon, Ian M C.

Afiliação

Landry N; Department of Physiology and Pathophysiology, Institute of Cardiovascular Sciences, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Kavosh MS; Department of Physiology and Pathophysiology, Institute of Cardiovascular Sciences, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Filomeno KL; Department of Physiology and Pathophysiology, Institute of Cardiovascular Sciences, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Rattan SG; Department of Physiology and Pathophysiology, Institute of Cardiovascular Sciences, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Czubryt MP; Department of Physiology and Pathophysiology, Institute of Cardiovascular Sciences, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Dixon IMC; Department of Physiology and Pathophysiology, Institute of Cardiovascular Sciences, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.

Physiol Rep ; 6(22): e13897, 2018 Nov.

Article em En | MEDLINE | ID: mdl-30488595

Assuntos

Metaloproteinase 9 da Matriz/metabolismo; Miocárdio/citologia; Miofibroblastos/metabolismo; Proteínas Proto-Oncogênicas/metabolismo; Actinas/genética; Actinas/metabolismo; Animais; Movimento Celular; Células Cultivadas; Fibronectinas/genética; Fibronectinas/metabolismo; Masculino; Metaloproteinase 9 da Matriz/genética; Miocárdio/metabolismo; Miofibroblastos/fisiologia; Paxilina/genética; Paxilina/metabolismo; Proteínas Proto-Oncogênicas/genética; Ratos; Ratos Sprague-Dawley

Palavras-chave

Cardiac fibroblast; MMP9; Ski; cardiac fibrosis; cell migration; fibroblast activation; myofibroblast

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas / Metaloproteinase 9 da Matriz / Miofibroblastos / Miocárdio Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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