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Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude.
Haji-Ghassemi, Omid; Müller-Loennies, Sven; Brooks, Cory L; MacKenzie, C Roger; Caveney, Nathanael; Van Petegem, Filip; Brade, Lore; Kosma, Paul; Brade, Helmut; Evans, Stephen V.
Afiliação
  • Haji-Ghassemi O; Department of Biochemistry and Microbiology , University of Victoria , P.O. Box 3055 STN CSC, Victoria , British Columbia , Canada V8P 3P6.
  • Müller-Loennies S; Research Center Borstel , Leibniz Lung Center , Parkallee 22 , Borstel D-23845 , Germany.
  • Brooks CL; Department of Chemistry , Fresno State University , 2555 East San Ramon Avenue, MS SB70 , Fresno , California 93740 , United States.
  • MacKenzie CR; Human Health Therapeutics Portfolio , National Research Council Canada , 100 Sussex Drive , Ottawa , Ontario , Canada K1A 0R6.
  • Caveney N; Department of Biochemistry and Microbiology , University of Victoria , P.O. Box 3055 STN CSC, Victoria , British Columbia , Canada V8P 3P6.
  • Van Petegem F; Department of Chemistry , University of Natural Resources and Life Sciences , A-1190 Vienna , Austria.
  • Brade L; Research Center Borstel , Leibniz Lung Center , Parkallee 22 , Borstel D-23845 , Germany.
  • Kosma P; Department of Chemistry , University of Natural Resources and Life Sciences , A-1190 Vienna , Austria.
  • Brade H; Research Center Borstel , Leibniz Lung Center , Parkallee 22 , Borstel D-23845 , Germany.
  • Evans SV; Department of Biochemistry and Microbiology , University of Victoria , P.O. Box 3055 STN CSC, Victoria , British Columbia , Canada V8P 3P6.
Biochemistry ; 58(6): 714-726, 2019 02 12.
Article em En | MEDLINE | ID: mdl-30571096
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligossacarídeos / Chlamydiaceae / Anticorpos Monoclonais Murinos / Epitopos Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligossacarídeos / Chlamydiaceae / Anticorpos Monoclonais Murinos / Epitopos Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article