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Rhein, An Anthraquinone Drug, Suppresses the NLRP3 Inflammasome and Macrophage Activation in Urate Crystal-Induced Gouty Inflammation.
Chang, Wan-Chun; Chu, Mu-Tzu; Hsu, Chih-Yuan; Wu, Yeong-Jian Jan; Lee, Jing-Yi; Chen, Ting-Jui; Chung, Wen-Hung; Chen, Der-Yuan; Hung, Shuen-Iu.
Afiliação
  • Chang WC; * Institute of Pharmacology, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
  • Chu MT; * Institute of Pharmacology, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
  • Hsu CY; * Institute of Pharmacology, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
  • Wu YJ; † Department of Medicine, Division of Allergy, Immunology and Rheumatology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Keelung, Taiwan.
  • Lee JY; ‡ Twi Biotechnology, Inc., Taipei, Taiwan.
  • Chen TJ; * Institute of Pharmacology, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
  • Chung WH; § Department of Dermatology, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan.
  • Chen DY; ¶ Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, College of Medicine and Chang Gung University, Taipei, Taiwan.
  • Hung SI; ∥ Rheumatology and Immunology Center, China Medical University Hospital; Department of Medicine, China Medical University, Taichung, Taiwan.
Am J Chin Med ; 47(1): 135-151, 2019.
Article em En | MEDLINE | ID: mdl-30612459

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Úrico / Artrite Gotosa / Supressores da Gota / Antraquinonas / Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR / Ativação de Macrófagos / Macrófagos / Fitoterapia / Anti-Inflamatórios Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Úrico / Artrite Gotosa / Supressores da Gota / Antraquinonas / Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR / Ativação de Macrófagos / Macrófagos / Fitoterapia / Anti-Inflamatórios Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article