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Cyclopamine tartrate, a modulator of hedgehog signaling and mitochondrial respiration, effectively arrests lung tumor growth and progression.
Kalainayakan, Sarada Preeta; Ghosh, Poorva; Dey, Sanchareeka; Fitzgerald, Keely E; Sohoni, Sagar; Konduri, Purna Chaitanya; Garrossian, Massoud; Liu, Li; Zhang, Li.
Afiliação
  • Kalainayakan SP; Department of Biological Sciences, University of Texas at Dallas, Richardson, TX, 75080, USA.
  • Ghosh P; Department of Biological Sciences, University of Texas at Dallas, Richardson, TX, 75080, USA.
  • Dey S; Department of Biological Sciences, University of Texas at Dallas, Richardson, TX, 75080, USA.
  • Fitzgerald KE; Department of Biological Sciences, University of Texas at Dallas, Richardson, TX, 75080, USA.
  • Sohoni S; Department of Biological Sciences, University of Texas at Dallas, Richardson, TX, 75080, USA.
  • Konduri PC; Department of Biological Sciences, University of Texas at Dallas, Richardson, TX, 75080, USA.
  • Garrossian M; Logan Natural Products, Plano, TX, 75025, USA.
  • Liu L; Department of Radiology, The University of Texas Southwestern Medical Center, Dallas, TX, 75390-9058, USA. Li.Liu@UTSouthwestern.edu.
  • Zhang L; Department of Biological Sciences, University of Texas at Dallas, Richardson, TX, 75080, USA. li.zhang@utdallas.edu.
Sci Rep ; 9(1): 1405, 2019 02 05.
Article em En | MEDLINE | ID: mdl-30723259
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tartaratos / Alcaloides de Veratrum / Carcinoma Pulmonar de Células não Pequenas / Proteínas Hedgehog / Carcinogênese / Neoplasias Pulmonares / Mitocôndrias Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tartaratos / Alcaloides de Veratrum / Carcinoma Pulmonar de Células não Pequenas / Proteínas Hedgehog / Carcinogênese / Neoplasias Pulmonares / Mitocôndrias Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article