Human Papillomavirus infection in senegalese female sex workers.
Papillomavirus Res
; 7: 97-101, 2019 06.
Article
em En
| MEDLINE
| ID: mdl-30771492
ABSTRACT
OBJECTIVES:
Several studies have documented the HPV genotypes in the Senegalese general population. The objective was to explore the HPV genotype distribution in Senegalese FSWs in order to assess the potential relevance of currently-available vaccines.METHODS:
Vaginal swabs samples collected as part of the National Integrated Biological and Behavioral Survey in 14 regions throughout the country were randomly selected for HPV testing using bead-based multiplex genotyping (TS-MPG).RESULTS:
Among the 436 FSW samples analyzed, the overall HPV prevalence was 79.8% (Nâ¯=â¯348), with 70.1% (Nâ¯=â¯244) cases presenting as multiple infections. High Risk HPV genotypes affecting at least 10% of FSWs included in order of decreasing frequency 52, 16, 35, 51, 33, 31, 18, and 45. Sixty-seven (15.4%) FSWs were HIV positive and they were significantly more affected by HPV (94% vs 77%; pâ¯<â¯0.01) than seronegative FSWs as well as infections with multiple genotype.CONCLUSION:
The present study indicates that FSW in Senegal experience a high burden of HPV infection with a high frequency of coinfection with HIV and multiple HPV genotypes. Public health interventions for this key population should include an earlier cervical dysplasia/cancer detection and preventative measures such as vaccination programs that must consider the HPV genotype distribution.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Papillomaviridae
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Infecções por Papillomavirus
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Profissionais do Sexo
/
Genótipo
Tipo de estudo:
Prevalence_studies
/
Risk_factors_studies
Limite:
Adolescent
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Adult
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Female
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Humans
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Middle aged
País/Região como assunto:
Africa
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article