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Association of Regulatory and Adaptive Status in Humans with Serotonergic Transmitter System Gene Polymorphism.
Pokrovskii, V M; Kashina, Yu V; Kiek, O V; Gumerova, O V; Gorbunova, V Yu; Abushkevich, V G; Penzhoyan, A G; Zabolotskikh, N V.
Afiliação
  • Pokrovskii VM; Department of Normal Physiology, Kuban State Medical University, Ministry of Health of the Russian Federation, Krasnodar, Russia. pokrovsky@ksma.ru.
  • Kashina YV; Department of Normal Physiology, Kuban State Medical University, Ministry of Health of the Russian Federation, Krasnodar, Russia.
  • Kiek OV; Department of Normal Physiology, Kuban State Medical University, Ministry of Health of the Russian Federation, Krasnodar, Russia.
  • Gumerova OV; Center for Molecular Genetic Studies, Department of Genetics, Bashkir State Pedagogical University, Ufa, Republic of Bashkortostan, Russia.
  • Gorbunova VY; Center for Molecular Genetic Studies, Department of Genetics, Bashkir State Pedagogical University, Ufa, Republic of Bashkortostan, Russia.
  • Abushkevich VG; Department of Normal Physiology, Kuban State Medical University, Ministry of Health of the Russian Federation, Krasnodar, Russia.
  • Penzhoyan AG; Department of Normal Physiology, Kuban State Medical University, Ministry of Health of the Russian Federation, Krasnodar, Russia.
  • Zabolotskikh NV; Department of Normal Physiology, Kuban State Medical University, Ministry of Health of the Russian Federation, Krasnodar, Russia.
Bull Exp Biol Med ; 166(4): 487-488, 2019 Feb.
Article em En | MEDLINE | ID: mdl-30783842
ABSTRACT
The regulatory and adaptive status was determined in 202 healthy subjects by the parameters of the cardiorespiratory synchronism probe. We performed molecular-genetic analysis of polymorphic variants of the main gene of serotonin biosynthesis, tryptophan hydroxylase TPH1 (A218C polymorphism) and TPH2 (G703T polymorphism), and serotonin receptors (HTR2C and HTR2A genes). The association of the regulatory and adaptive status of a subject with the polymorphism of serotonergic mediator system genes was revealed.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença Cardiopulmonar / Polimorfismo de Nucleotídeo Único Tipo de estudo: Risk_factors_studies Limite: Adolescent / Adult / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença Cardiopulmonar / Polimorfismo de Nucleotídeo Único Tipo de estudo: Risk_factors_studies Limite: Adolescent / Adult / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article