Successes and challenges for preventing measles, mumps and rubella by vaccination.
Curr Opin Virol
; 34: 110-116, 2019 02.
Article
em En
| MEDLINE
| ID: mdl-30852425
ABSTRACT
The measles, mumps and rubella (MMR) vaccine has an outstanding safety record and is highly efficacious. High coverage with MMR has led to the elimination of endemic measles, rubella, and congenital rubella syndrome in the US. The biggest challenges to global measles and rubella control and elimination are insufficient vaccination coverage globally and increasing hesitancy. Despite high two dose coverage rates, mumps has made a resurgence in the US and other countries. Mumps outbreaks have occurred primarily in close contact, high-density settings and most cases had received a second dose 10 or more years previously. Waning humoral immunity and antigenic variation of circulating wild-type mumps strains may play a role in the mumps resurgence.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Rubéola (Sarampo Alemão)
/
Vacina contra Sarampo-Caxumba-Rubéola
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Cobertura Vacinal
/
Sarampo
/
Caxumba
Limite:
Humans
País/Região como assunto:
America do norte
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article