Tropheryma whipplei intestinal colonization in Italian and migrant population: a retrospective observational study.
Future Microbiol
; 14: 283-292, 2019 03.
Article
em En
| MEDLINE
| ID: mdl-30855186
ABSTRACT
AIM:
To obtain the first molecular epidemiological survey of Tropheryma whipplei intestinal colonization in Italy. Materials &methods:
Retrospective, observational study to assess the prevalence of T. whipplei, the causative agent of Whipple's disease, in stool samples (real-time PCR) of patients attending the Center for Tropical Diseases (Italy) and risk factors associated.RESULTS:
Overall prevalence was 6.9% (85/1240). The younger age group showed a significantly higher rate than older age group (12.7 vs 5.9%, p = 0.002). The prevalence was 4.9% for Italians and 9.3% for migrants (p = 0.003). Among the latter, children less than 10 years had higher prevalence than older ones (17.3 vs 7.3%, p = 0.003). The young age, male gender and Giardia duodenalis and Entamoeba histolytica coinfection were risk factors.CONCLUSION:
Our study confirms an increased risk of acquiring T. whipplei infection during childhood, under poor sanitary conditions.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tropheryma
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Intestinos
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Doença de Whipple
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Aged80
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Child
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Child, preschool
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Female
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Humans
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Infant
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Male
País/Região como assunto:
Europa
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article