Icariin protects vascular endothelial cells from oxidative stress through inhibiting endoplasmic reticulum stress.

Wang, Fang-Yuan; Jia, Jian; Song, Huan-Huan; Jia, Cheng-Ming; Chen, Chang-Bo; Ma, Jing

Wang, Fang-Yuan; Jia, Jian; Song, Huan-Huan; Jia, Cheng-Ming; Chen, Chang-Bo; Ma, Jing.

Afiliação

Wang FY; Department of Traditional Chinese Medicine, Army Medical Center in Traditional Chinese Medicine, Xijing Hospital, Forth Military Medical University, Xi'an 710032, Shaanxi Province, China.
Jia J; Department of Traditional Chinese Medicine, Army Medical Center in Traditional Chinese Medicine, Xijing Hospital, Forth Military Medical University, Xi'an 710032, Shaanxi Province, China.
Song HH; Department of Traditional Chinese Medicine, Army Medical Center in Traditional Chinese Medicine, Xijing Hospital, Forth Military Medical University, Xi'an 710032, Shaanxi Province, China.
Jia CM; Department of Traditional Chinese Medicine, Army Medical Center in Traditional Chinese Medicine, Xijing Hospital, Forth Military Medical University, Xi'an 710032, Shaanxi Province, China.
Chen CB; Department of Traditional Chinese Medicine, Army Medical Center in Traditional Chinese Medicine, Xijing Hospital, Forth Military Medical University, Xi'an 710032, Shaanxi Province, China.
Ma J; Department of Traditional Chinese Medicine, Army Medical Center in Traditional Chinese Medicine, Xijing Hospital, Forth Military Medical University, Xi'an 710032, Shaanxi Province, China. Electronic address: jingma@fmmu.edu.cn.

J Integr Med ; 17(3): 205-212, 2019 May.

Article em En | MEDLINE | ID: mdl-30890424

Assuntos

Estresse do Retículo Endoplasmático/efeitos dos fármacos; Células Endoteliais/efeitos dos fármacos; Flavonoides/farmacologia; Estresse Oxidativo/efeitos dos fármacos; Substâncias Protetoras/farmacologia; Apoptose/efeitos dos fármacos; Chaperona BiP do Retículo Endoplasmático; Células Endoteliais/citologia; Células Endoteliais/metabolismo; Glutationa Peroxidase/genética; Glutationa Peroxidase/metabolismo; Proteínas de Choque Térmico/genética; Proteínas de Choque Térmico/metabolismo; Peróxido de Hidrogênio/toxicidade; Espécies Reativas de Oxigênio/metabolismo; Superóxido Dismutase/genética; Superóxido Dismutase/metabolismo

Palavras-chave

Endoplasmic reticulum stress; Human umbilical vein endothelial cells; Icariin; Oxidative stress

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Flavonoides / Estresse Oxidativo / Substâncias Protetoras / Células Endoteliais / Estresse do Retículo Endoplasmático Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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