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Targeting ß-catenin overcomes MEK inhibition resistance in colon cancer with KRAS and PIK3CA mutations.
Moon, Jai-Hee; Hong, Seung-Woo; Kim, Jeong Eun; Shin, Jae-Sik; Kim, Jin-Sun; Jung, Soo-A; Ha, Seung Hee; Lee, Seul; Kim, Joseph; Lee, Dae Hee; Park, Yoon Sun; Kim, Dong Min; Park, Sang-Soo; Hong, Jun Ki; Kim, Do Yeon; Kim, Eun Ho; Jung, Joonyee; Kim, Mi Jin; Kim, Seung-Mi; Deming, Dustin A; Kim, Kyunggon; Kim, Tae Won; Jin, Dong-Hoon.
Afiliação
  • Moon JH; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.
  • Hong SW; Department of Medical Science, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
  • Kim JE; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.
  • Shin JS; Department of Convergence Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
  • Kim JS; Department of Oncology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
  • Jung SA; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.
  • Ha SH; Department of Convergence Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
  • Lee S; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.
  • Kim J; Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
  • Lee DH; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.
  • Park YS; Department of Convergence Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
  • Kim DM; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.
  • Park SS; Department of Convergence Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
  • Hong JK; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.
  • Kim DY; Department of Convergence Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
  • Kim EH; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.
  • Jung J; Department of Medical Science, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
  • Kim MJ; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.
  • Kim SM; Department of Convergence Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
  • Deming DA; Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.
  • Kim K; Department of Medical Science, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
  • Kim TW; Department of Medical Science, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
  • Jin DH; Department of Medical Science, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
Br J Cancer ; 120(9): 941-951, 2019 04.
Article em En | MEDLINE | ID: mdl-30944457
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas p21(ras) / Neoplasias do Colo / MAP Quinase Quinase 1 / MAP Quinase Quinase 3 / Inibidores de Proteínas Quinases / Beta Catenina / Classe I de Fosfatidilinositol 3-Quinases Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas p21(ras) / Neoplasias do Colo / MAP Quinase Quinase 1 / MAP Quinase Quinase 3 / Inibidores de Proteínas Quinases / Beta Catenina / Classe I de Fosfatidilinositol 3-Quinases Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article