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Hopelessness and Other Depressive Symptoms in Adults 70 Years and Older as Predictors of All-Cause Mortality Within 3 Months After Acute Hospitalization: The Hospital-ADL Study.
Reichardt, Lucienne A; Nederveen, Floor E; van Seben, Rosanne; Aarden, Jesse J; van der Schaaf, Marike; Engelbert, Raoul H H; van der Esch, Martin; Henstra, Marieke J; Twisk, Jos W R; Bosch, Jos A; Buurman, Bianca M.
Afiliação
  • Reichardt LA; From the Department of Internal Medicine (Reichardt, Nederveen, van Seben, Henstra, Buurman), Section of Geriatric Medicine, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam; Department of Rehabilitation (Aarden, van der Schaaf, Engelbert), Amsterdam Movement Sciences, Amsterdam UMC, University of Amsterdam; ACHIEVE - Center of Applied Research (Aarden, Engelbert, van der Esch, Buurman), Faculty of Health, Amsterdam University of Applied Sciences; Reade (Esch),
Psychosom Med ; 81(5): 477-485, 2019 06.
Article em En | MEDLINE | ID: mdl-30985404
ABSTRACT

OBJECTIVE:

Depression among older adults predicts mortality after acute hospitalization. Depression is highly heterogeneous in its presentation of symptoms, whereas individual symptoms may differ in predictive value. This study aimed to investigate the prevalence of individual cognitive-affective depressive symptoms during acute hospitalization and investigate the predictive value of both overall and individual cognitive-affective depressive symptoms for mortality between admission up to 3-month postdischarge among older patients.

METHODS:

A prospective multicenter cohort study enrolled 401 acutely hospitalized patients 70 years and older (Hospitalization-Associated Disability and impact on daily Life Study). The predictive value of depressive symptoms, assessed using the Geriatric Depression Scale 15, during acute hospitalization on mortality was analyzed with multiple logistic regression.

RESULTS:

The analytic sample included 398 patients (M (SD) = 79.6 (6.6) years; 51% men). Results showed that 9.3% of participants died within 3 months, with symptoms of apathy being most frequently reported. The depression total score during hospitalization was associated with increased mortality risk (admission odds ratio [OR] = 1.2, 95% confidence interval [CI] = 1.2-1.3; discharge OR = 1.2, 95% CI = 1.2-1.4). Stepwise multiple logistic regression analyses yielded the finding that feelings of hopelessness during acute hospitalization were a strong unique predictor of mortality (admission OR = 3.6, 95% CI = 1.8-7.4; discharge OR = 5.7, 95% CI = 2.5-13.1). These associations were robust to adjustment for demographic factors, somatic symptoms, and medical comorbidities.

CONCLUSIONS:

Symptoms of apathy were most frequently reported in response to acute hospitalization. However, feelings of hopelessness about their situation were the strongest cognitive-affective predictor of mortality. These results imply that this item is important in identifying patients who are in the last phase of their lives and for whom palliative care may be important.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Alta do Paciente / Escalas de Graduação Psiquiátrica / Envelhecimento / Avaliação Geriátrica / Causas de Morte / Depressão / Apatia / Esperança Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Alta do Paciente / Escalas de Graduação Psiquiátrica / Envelhecimento / Avaliação Geriátrica / Causas de Morte / Depressão / Apatia / Esperança Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article