Acute Promyelocytic Leukemia and HIV: Case Reports and a Review of the Literature.
Intern Med
; 58(16): 2387-2391, 2019 Aug 15.
Article
em En
| MEDLINE
| ID: mdl-31118366
ABSTRACT
Acute promyelocytic leukemia (APL) in human immunodeficiency virus (HIV)-infected individuals is very rare. There is currently no consensus regarding the use of anti-cancer drugs with highly active anti-retroviral therapy (ART) in these patients due to their small number. We herein report two cases of APL with HIV-infected patients. Both cases received all-trans-retinoic acid-containing chemotherapies and achieved complete remission. ART was continued throughout the treatment course. The clinical course of these cases suggests that it is preferable to perform standard chemotherapy for APL with ART if patients have an adequate performance status.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tretinoína
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Leucemia Promielocítica Aguda
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Protocolos de Quimioterapia Combinada Antineoplásica
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Infecções por HIV
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Terapia Antirretroviral de Alta Atividade
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
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Humans
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Male
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article