Evaluation of attention in APP/PS1 mice shows impulsive and compulsive behaviours.

Shepherd, Amy; May, Carlos; Churilov, Leonid; Adlard, Paul A; Hannan, Anthony J; Burrows, Emma L

Shepherd, Amy; May, Carlos; Churilov, Leonid; Adlard, Paul A; Hannan, Anthony J; Burrows, Emma L.

Afiliação

Shepherd A; Florey Institute of Neuroscience and Mental Health, Kenneth Myer Building, University of Melbourne, Parkville, Victoria, Australia.
May C; Florey Institute of Neuroscience and Mental Health, Kenneth Myer Building, University of Melbourne, Parkville, Victoria, Australia.
Churilov L; Florey Institute of Neuroscience and Mental Health, Melbourne Brain Centre, Heidelberg, Victoria, Australia.
Adlard PA; Florey Institute of Neuroscience and Mental Health, Kenneth Myer Building, University of Melbourne, Parkville, Victoria, Australia.
Hannan AJ; Florey Institute of Neuroscience and Mental Health, Kenneth Myer Building, University of Melbourne, Parkville, Victoria, Australia.
Burrows EL; Department of Anatomy and Neuroscience, University of Melbourne, Parkville, Victoria, Australia.

Genes Brain Behav ; 20(1): e12594, 2021 01.

Article em En | MEDLINE | ID: mdl-31177612

Assuntos

Doença de Alzheimer/psicologia; Precursor de Proteína beta-Amiloide/genética; Atenção; Comportamento Compulsivo/genética; Presenilina-1/genética; Doença de Alzheimer/genética; Animais; Comportamento Compulsivo/fisiopatologia; Masculino; Camundongos; Camundongos Endogâmicos C57BL

Palavras-chave

5-choice serial reaction time task; APP/PS1 mouse; Alzheimer's disease; attention; compulsive behaviour; dementia; impulsive behaviour; mice; preclinical animal model; touchscreen

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Atenção / Precursor de Proteína beta-Amiloide / Comportamento Compulsivo / Presenilina-1 / Doença de Alzheimer Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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