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P-Glycoprotein-Mediated Efflux Reduces the In Vivo Efficacy of a Therapeutic Targeting the Gastrointestinal Parasite Cryptosporidium.
Arnold, Samuel L M; Choi, Ryan; Hulverson, Matthew A; Whitman, Grant R; Mccloskey, Molly C; Dorr, Carlie S; Vidadala, Rama S R; Khatod, Mansi; Morada, Mary; Barrett, Lynn K; Maly, Dustin J; Yarlett, Nigel; Van Voorhis, Wesley C.
Afiliação
  • Arnold SLM; Division of Allergy and Infectious Disease, Department of Medicine, University of Washington, Seattle.
  • Choi R; Center for Emerging and Reemerging Infectious Disease, University of Washington, Seattle.
  • Hulverson MA; Division of Allergy and Infectious Disease, Department of Medicine, University of Washington, Seattle.
  • Whitman GR; Center for Emerging and Reemerging Infectious Disease, University of Washington, Seattle.
  • Mccloskey MC; Division of Allergy and Infectious Disease, Department of Medicine, University of Washington, Seattle.
  • Dorr CS; Center for Emerging and Reemerging Infectious Disease, University of Washington, Seattle.
  • Vidadala RSR; Division of Allergy and Infectious Disease, Department of Medicine, University of Washington, Seattle.
  • Khatod M; Center for Emerging and Reemerging Infectious Disease, University of Washington, Seattle.
  • Morada M; Division of Allergy and Infectious Disease, Department of Medicine, University of Washington, Seattle.
  • Barrett LK; Center for Emerging and Reemerging Infectious Disease, University of Washington, Seattle.
  • Maly DJ; Division of Allergy and Infectious Disease, Department of Medicine, University of Washington, Seattle.
  • Yarlett N; Center for Emerging and Reemerging Infectious Disease, University of Washington, Seattle.
  • Van Voorhis WC; Department of Chemistry, University of Washington, Seattle.
J Infect Dis ; 220(7): 1188-1198, 2019 08 30.
Article em En | MEDLINE | ID: mdl-31180118
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperidinas / Pirazóis / Pirimidinas / Quinolinas / Membro 1 da Subfamília B de Cassetes de Ligação de ATP / Criptosporidiose / Cryptosporidium / Enteropatias Parasitárias / Naftalenos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperidinas / Pirazóis / Pirimidinas / Quinolinas / Membro 1 da Subfamília B de Cassetes de Ligação de ATP / Criptosporidiose / Cryptosporidium / Enteropatias Parasitárias / Naftalenos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article