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Lack of Association Between the S83I ParC Mutation in Mycoplasma genitalium and Treatment Outcomes Among Men Who Have Sex With Men with Nongonococcal Urethritis.
Chambers, Laura C; Jensen, Jørgen S; Morgan, Jennifer L; Lowens, M Sylvan; Romano, Sarah S; Totten, Patricia A; Soge, Olusegun O; Hughes, James P; Golden, Matthew R; Manhart, Lisa E.
Afiliação
  • Chambers LC; From the Department of Epidemiology, University of Washington, Seattle, WA.
  • Jensen JS; Statens Serum Institut, Copenhagen, Denmark.
  • Morgan JL; HIV/STD Program, Public Health-Seattle and King County.
  • Lowens MS; HIV/STD Program, Public Health-Seattle and King County.
  • Romano SS; From the Department of Epidemiology, University of Washington, Seattle, WA.
  • Totten PA; Department of Medicine.
  • Soge OO; Department of Global Health.
  • Hughes JP; Department of Medicine.
  • Golden MR; Department of Global Health.
  • Manhart LE; Department of Biostatistics, University of Washington, Seattle, WA.
Sex Transm Dis ; 46(12): 805-809, 2019 12.
Article em En | MEDLINE | ID: mdl-31259853
From February 2015 to October 2017, among 20 men who have sex with men with Mycoplasma genitalium-associated nongonococcal urethritis, 15% had macrolide resistance and S83I ParC mutations. Azithromycin followed by moxifloxacin cleared Mycoplasma genitalium in 2 of 2 with and 11 of 13 without S83I mutations. Dual failures were cleared after doxycycline. S83I mutations were not associated with moxifloxacin failure.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Uretrite / Homossexualidade Masculina / DNA Topoisomerase IV / Mycoplasma genitalium / Antibacterianos / Infecções por Mycoplasma Tipo de estudo: Risk_factors_studies Limite: Adult / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Uretrite / Homossexualidade Masculina / DNA Topoisomerase IV / Mycoplasma genitalium / Antibacterianos / Infecções por Mycoplasma Tipo de estudo: Risk_factors_studies Limite: Adult / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article