Recurrent Herpes Zoster Ophthalmicus in a Patient With a Novel Toll-Like Receptor 3 Variant Linked to Compromised Activation Capacity in Fibroblasts.

Liang, Frank; Glans, Hedvig; Enoksson, Sara Lind; Kolios, Antonios G A; Loré, Karin; Nilsson, Jakob

Liang, Frank; Glans, Hedvig; Enoksson, Sara Lind; Kolios, Antonios G A; Loré, Karin; Nilsson, Jakob.

Afiliação

Liang F; Division of Immunology and Allergy, Department of Medicine Solna.
Glans H; Center for Molecular Medicine.
Enoksson SL; Division of Dermatology and Venerology, Department of Medicine Solna, Karolinska University Hospital, Stockholm, Sweden.
Kolios AGA; Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Loré K; Department of Clinical Immunology, Karolinska University Hospital, Huddinge, Sweden.
Nilsson J; Department of Immunology, University Hospital Zurich, Switzerland.

J Infect Dis ; 221(8): 1295-1303, 2020 03 28.

Article em En | MEDLINE | ID: mdl-31268141

Assuntos

Herpes Zoster Oftálmico/virologia; Herpesvirus Humano 3/patogenicidade; Mutação/genética; Receptor 3 Toll-Like/genética; Adulto; Encefalite por Herpes Simples/genética; Encefalite por Herpes Simples/virologia; Feminino; Fibroblastos/virologia; Herpes Zoster/genética; Herpes Zoster/virologia; Herpes Zoster Oftálmico/genética; Humanos; Hospedeiro Imunocomprometido/genética

Palavras-chave

TLR3; Toll-like receptor 3; VZV; dominant-negative mutation; innate immunity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Herpes Zoster Oftálmico / Herpesvirus Humano 3 / Receptor 3 Toll-Like / Mutação Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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