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Single systemic transfer of a human gene associated with exceptional longevity halts the progression of atherosclerosis and inflammation in ApoE knockout mice through a CXCR4-mediated mechanism.
Puca, Annibale Alessandro; Carrizzo, Albino; Spinelli, Chiara; Damato, Antonio; Ambrosio, Mariateresa; Villa, Francesco; Ferrario, Anna; Maciag, Anna; Fornai, Francesco; Lenzi, Paola; Valenti, Valentina; di Nonno, Flavio; Accarino, Giulio; Madonna, Michele; Forte, Maurizio; Calì, Gaetano; Baragetti, Andrea; Norata, Giuseppe Danilo; Catapano, Alberico Luigi; Cattaneo, Monica; Izzo, Raffaele; Trimarco, Valentina; Montella, Francesco; Versaci, Francesco; Auricchio, Alberto; Frati, Giacomo; Sciarretta, Sebastiano; Madeddu, Paolo; Ciaglia, Elena; Vecchione, Carmine.
Afiliação
  • Puca AA; Ageing Unit, IRCCS MultiMedica, Via G. Fantoli 16/15, 20138 Milan, Italy.
  • Carrizzo A; Department of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana" University of Salerno, Via S. Allende, 84081 Baronissi (SA), Italy.
  • Spinelli C; IRCCS Neuromed, Loc. Camerelle, 86077 Pozzilli (IS), Italy.
  • Damato A; Ageing Unit, IRCCS MultiMedica, Via G. Fantoli 16/15, 20138 Milan, Italy.
  • Ambrosio M; IRCCS Neuromed, Loc. Camerelle, 86077 Pozzilli (IS), Italy.
  • Villa F; IRCCS Neuromed, Loc. Camerelle, 86077 Pozzilli (IS), Italy.
  • Ferrario A; Ageing Unit, IRCCS MultiMedica, Via G. Fantoli 16/15, 20138 Milan, Italy.
  • Maciag A; Ageing Unit, IRCCS MultiMedica, Via G. Fantoli 16/15, 20138 Milan, Italy.
  • Fornai F; Ageing Unit, IRCCS MultiMedica, Via G. Fantoli 16/15, 20138 Milan, Italy.
  • Lenzi P; IRCCS Neuromed, Loc. Camerelle, 86077 Pozzilli (IS), Italy.
  • Valenti V; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, via Roma 55, 56126 Pisa, Italy.
  • di Nonno F; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, via Roma 55, 56126 Pisa, Italy.
  • Accarino G; UOC Cardiologia Ospedale Santa Maria Goretti, 04100 Latina, Italy.
  • Madonna M; IRCCS Neuromed, Loc. Camerelle, 86077 Pozzilli (IS), Italy.
  • Forte M; Department of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana" University of Salerno, Via S. Allende, 84081 Baronissi (SA), Italy.
  • Calì G; IRCCS Neuromed, Loc. Camerelle, 86077 Pozzilli (IS), Italy.
  • Baragetti A; IRCCS Neuromed, Loc. Camerelle, 86077 Pozzilli (IS), Italy.
  • Norata GD; Department of Endocrinology and Experimental Oncology Institute, CNR, Via Sergio Pansini, 80131 Naples, Italy.
  • Catapano AL; Department of Pharmacological and Biomolecular Sciences, Università Degli Studi di Milano, via Vanvitelli 32, 20129 Milan, Italy.
  • Cattaneo M; Department of Pharmacological and Biomolecular Sciences, Università Degli Studi di Milano, via Vanvitelli 32, 20129 Milan, Italy.
  • Izzo R; Società Italiana per lo Studio della Arteriosclerosi (SISA) Centro Aterosclerosi, Bassini Hospital, Cinisello Balsamo, 20092 Milan, Italy.
  • Trimarco V; Department of Pharmacological and Biomolecular Sciences, Università Degli Studi di Milano, via Vanvitelli 32, 20129 Milan, Italy.
  • Montella F; IRCCS Multimedica Hospital, 20099 Sesto San Giovanni Milan, Italy.
  • Versaci F; Ageing Unit, IRCCS MultiMedica, Via G. Fantoli 16/15, 20138 Milan, Italy.
  • Auricchio A; Department of Advanced Biomedical Sciences, University Federico II of Naples, 80131 Naples, Italy.
  • Frati G; Department of Advanced Biomedical Sciences, University Federico II of Naples, 80131 Naples, Italy.
  • Sciarretta S; Department of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana" University of Salerno, Via S. Allende, 84081 Baronissi (SA), Italy.
  • Madeddu P; UOC Cardiologia Ospedale Santa Maria Goretti, 04100 Latina, Italy.
  • Ciaglia E; Department of Cardiovascular Disease, Tor Vergata University of Rome, 00133 Rome, Italy.
  • Vecchione C; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli (Na), Italy.
Eur Heart J ; 41(26): 2487-2497, 2020 07 07.
Article em En | MEDLINE | ID: mdl-31289820
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aterosclerose / Placa Aterosclerótica Tipo de estudo: Risk_factors_studies Limite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aterosclerose / Placa Aterosclerótica Tipo de estudo: Risk_factors_studies Limite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article