Identification and validation of a prognostic four-genes signature for hepatocellular carcinoma: integrated ceRNA network analysis.

Yan, Yongcong; Lu, Yingjuan; Mao, Kai; Zhang, Mengyu; Liu, Haohan; Zhou, Qianlei; Lin, Jianhong; Zhang, Jianlong; Wang, Jie; Xiao, Zhiyu

Yan, Yongcong; Lu, Yingjuan; Mao, Kai; Zhang, Mengyu; Liu, Haohan; Zhou, Qianlei; Lin, Jianhong; Zhang, Jianlong; Wang, Jie; Xiao, Zhiyu.

Afiliação

Yan Y; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
Lu Y; Department of Hepatobiliary Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Yanjiang West Road 107#, Guangzhou, 510120, China.
Mao K; RNA Biomedical Institute, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
Zhang M; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
Liu H; Department of Oral and Maxillofacial Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
Zhou Q; RNA Biomedical Institute, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
Lin J; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
Zhang J; Department of Hepatobiliary Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Yanjiang West Road 107#, Guangzhou, 510120, China.
Wang J; RNA Biomedical Institute, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
Xiao Z; Department of Gastroenterology and Hepatology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.

Hepatol Int ; 13(5): 618-630, 2019 Sep.

Article em En | MEDLINE | ID: mdl-31321712

Assuntos

Carcinoma Hepatocelular/genética; Genes/genética; Neoplasias Hepáticas/genética; RNA/genética; Proteínas Adaptadoras de Transdução de Sinal/genética; Carcinoma Hepatocelular/diagnóstico; Carcinoma Hepatocelular/mortalidade; Feminino; Regulação Neoplásica da Expressão Gênica/genética; Humanos; Neoplasias Hepáticas/diagnóstico; Neoplasias Hepáticas/mortalidade; Masculino; Pessoa de Meia-Idade; Quinases de Proteína Quinase Ativadas por Mitógeno/genética; Complexo Repressor Polycomb 1/genética; Prognóstico; Modelos de Riscos Proporcionais; Proteínas de Ligação a RNA/genética; Reação em Cadeia da Polimerase em Tempo Real; Análise de Sobrevida

Palavras-chave

Competing endogenous RNA; Global transcriptome; Hepatocellular carcinoma; Least absolute shrinkage and selection operator; Overall survival

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA / Carcinoma Hepatocelular / Genes / Neoplasias Hepáticas Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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