Bone marrow macrophage M2 polarization and adipose-derived stem cells osteogenic differentiation synergistically promote rehabilitation of bone damage.

Li, Yiyang; Kong, Ning; Li, Zhe; Tian, Run; Liu, Xiaohui; Liu, Guanzhi; Wang, Kunzheng; Yang, Pei

Li, Yiyang; Kong, Ning; Li, Zhe; Tian, Run; Liu, Xiaohui; Liu, Guanzhi; Wang, Kunzheng; Yang, Pei.

Afiliação

Li Y; Department of Bone and Joint Surgery, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an, Shannxi Province, 710004, China.
Kong N; Department of Bone and Joint Surgery, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an, Shannxi Province, 710004, China.
Li Z; Department of Bone and Joint Surgery, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an, Shannxi Province, 710004, China.
Tian R; Department of Bone and Joint Surgery, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an, Shannxi Province, 710004, China.
Liu X; Department of Bone and Joint Surgery, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an, Shannxi Province, 710004, China.
Liu G; Department of Bone and Joint Surgery, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an, Shannxi Province, 710004, China.
Wang K; Department of Bone and Joint Surgery, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an, Shannxi Province, 710004, China.
Yang P; Department of Bone and Joint Surgery, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an, Shannxi Province, 710004, China.

J Cell Biochem ; 120(12): 19891-19901, 2019 12.

Article em En | MEDLINE | ID: mdl-31338874

Assuntos

Fêmur/lesões; Macrófagos/citologia; Células-Tronco Mesenquimais/citologia; Osteogênese; Animais; Células da Medula Óssea/fisiologia; Diferenciação Celular; Polaridade Celular; Técnicas de Cocultura; Subunidade alfa 1 de Fator de Ligação ao Core/metabolismo; Modelos Animais de Doenças; Macrófagos/fisiologia; Masculino; Células-Tronco Mesenquimais/fisiologia; Camundongos Endogâmicos C57BL; Osteoprotegerina/metabolismo; Fator de Transcrição Sp7/metabolismo; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

adipose tissue-derived mesenchymal stem cells; bone marrow-derived macrophages; cell polarity; differentiation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteogênese / Fêmur / Células-Tronco Mesenquimais / Macrófagos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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